Sökning: "glucose variability"

Visar resultat 21 - 25 av 39 avhandlingar innehållade orden glucose variability.

  1. 21. Genetics of type 2 diabetes and the metabolic syndrome

    Författare :Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. LÄS MER

  3. 22. Proteomics informed investigation of human hepatocytes and liver tissue

    Författare :Niklas Handin; Per Artursson; Peter Nygren; Tobias Sjöblom; Mårten Fryknäs; Pieter Annaert; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; liver; hepatocytes; proteomics; cellular stress; apoptosis; hepatotoxicity; 3D culture; spheroid; drug metabolism; drug toxicity; drug transport; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : A successful drug needs to display beneficial absorption, distribution, metabolism, excretion and toxicity (ADME-Tox) profile. It is therefore important to investigate these properties during the drug discovery process. LÄS MER

  4. 23. Diabetes under seven (DU7). Aspects of glycaemic control, hypoglycaemia, nutrition and physical activity in children younger than seven years with type 1 diabetes mellitus

    Författare :Frida Sundberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preschool children; type 1 diabetes; glycaemic control; hypoglycaemia; nutrition; physical activity; health-related quality of life;

    Sammanfattning : Aim: The aim of this thesis is to elucidate the specific challenges in insulin treatment for children younger than seven years with type 1 diabetes, with a focus on glycaemic control, hypoglycaemia, nutrition and physical activity. Methods: There were 24 children younger than seven years with type 1 diabetes and 27 healthy children from Gothenburg in the observational study that forms the basis of this thesis. LÄS MER

  5. 24. Ultrasound assessment of carotid atherosclerosis focusing on plaque characteristics and changes over time

    Författare :Ulrica Prahl; Göteborgs universitet; []
    Nyckelord :Ultrasound; Carotid artery; Women; Plaques; Echogenicity; Atherosclerosis;

    Sammanfattning : In a clinical perspective better methods to identify subjects at increased cardiovascular risk are needed. Atherosclerotic plaques of the carotid arteries with low echogenicity have been related to future clinical events. LÄS MER

  7. 25. Brain-gut-adipose interplay in the antidiabetic effects of gastric bypass surgery

    Författare :Kristina Almby; Jan Eriksson; Bo Ahrén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Medicinsk vetenskap; Medical Science; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Gastric bypass surgery (GBP) leads not only to considerable and consistent weight loss but to a number of beneficial metabolic effects, often including a swift remission of type 2 diabetes (T2DM). Increases in the gut hormone GLP-1 are considered central to this effect, although several other mechanism are likely involved. LÄS MER