Sökning: "genetic modification"

Visar resultat 1 - 5 av 120 avhandlingar innehållade orden genetic modification.

  1. 1. Stiffness modification of tensegrity structures

    Författare :Seif Dalilsafaei; Anders Eriksson; Karl-Gunnar Olsson; KTH; []
    Nyckelord :tensegrity; boom; finite element analysis; genetic algorithm; flexibility analysis; active structure; TECHNOLOGY; TEKNIKVETENSKAP;

    Sammanfattning : Although the concept of tensegrity structures was invented in the beginning of the twentieth century, the applications of these structures are limited, partially due to their low stiffness. The stiffness of tensegrities comes from topology, configuration, pre-stress and initial axial element stiffnesses. LÄS MER

  3. 2. Genetic and Epigenetic Characterisation of Breast Tumours

    Författare :Karolina Holm; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; PIK3CA; PTEN; PI3K pathway; CCND1; microarrays; molecular subtypes; DNA methylation; EZH2; H3K27me3; PRC2; histone modification;

    Sammanfattning : Breast tumours harbour a large amount of genetic and epigenetic alterations, which are associated with e.g. tumour aggressiveness, prognosis, and response to therapy. LÄS MER

  4. 3. Genetic pathways controlling CNS development : The role of Notch signaling in regulating daughter cell proliferation in Drosophila

    Författare :Caroline Bivik Stadler; Stefan Thor; Jan-Ingvar Jönsson; Allison Bardin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The human central nervous system (CNS) displays the greatest cellular diversity of any organ system, consisting of billions of neurons, of numerous cell sub-types, interconnected in a vast network. Given this enormous complexity, decoding the genetic programs controlling the multistep process of CNS development remains a major challenge. LÄS MER

  5. 4. Genetic modification and mesodermal differentiation of human embryonic stem cells

    Författare :Christian Unger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Pluripotent human embryonic stem cells (hESCs) are a resource of great potential, available for research. Their capability to differentiate into any cell of the human body and an unlimited in vitro expansion offers the possibility to study the earliest human development and provides a source of cells for regenerative medicine. LÄS MER

  7. 5. Genetic modification of cholera toxin B subunit for mucosal anti-infectious or anti-pathologic vaccination

    Författare :Hamid Sadeghi; Göteborgs universitet; []
    Nyckelord :Genetic fusion protein; cholera toxin B subunit; insulin; GST; Oral tolerance;

    Sammanfattning : The development of mucosal vaccines requires antigen delivery systems that can efficiently help to present vaccine antigens to the mucosal immune system. En efficient and well known antigen carrier/delivery system is the B subunit of cholera toxin (CTB). LÄS MER