Sökning: "Karolina Holm"

Hittade 2 avhandlingar innehållade orden Karolina Holm.

  1. 1. Genetic and Epigenetic Characterisation of Breast Tumours

    Författare :Karolina Holm; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; PIK3CA; PTEN; PI3K pathway; CCND1; microarrays; molecular subtypes; DNA methylation; EZH2; H3K27me3; PRC2; histone modification;

    Sammanfattning : Breast tumours harbour a large amount of genetic and epigenetic alterations, which are associated with e.g. tumour aggressiveness, prognosis, and response to therapy. LÄS MER

  3. 2. Estrogen receptor β signalling in mammary epithelial and breast cancer cells

    Författare :Karolina Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens are key players in the etiology and progression of breast cancer, and mediate their effects through the estrogen receptors (ERα and ERβ). ERα plays important roles in proliferation and progression of breast cancer, whereas a distinct function of ERβ in the initiation and development of breast cancer is not yet clearly established. LÄS MER