Sökning: "gene polymorphisms"

Visar resultat 16 - 20 av 415 avhandlingar innehållade orden gene polymorphisms.

  1. 16. Pharmacogenetic Studies of Antihypertensive Treatment : With Special Reference to the Renin-Angiotensin-Aldosterone System

    Författare :Lisa Kurland; Heribert Schunkert; Uppsala universitet; []
    Nyckelord :Medical sciences; pharmacogenetics; hypertension; renin-angiotension-aldosterone system; gene polymorphisms; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Hypertension is common and constitutes an increased risk of morbidity and mortality of cardiovascular disease. Antihypertensive treatment will reduce this risk; the individual patient's response to treatment, however, is difficult to predict. LÄS MER

  3. 17. Gene Expression in Cancer Cells : Detection of Splice Variants, Allele-specific Expression and DNA Methylation

    Författare :Lili Milani; Ann-Christine Syvänen; Thomas R. Gingeras; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : The human genome sequencing project has provided a wealth of information on sequence variation between individuals. The surprisingly low number of genes in the human genome is compensated for by a complex regulation of gene expression. LÄS MER

  4. 18. Folates in the treatment of colorectal cancer

    Författare :Helena Taflin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Folate; Colorectal cancer; leucovorin; modufolin; LC-MS MS; polymorphisms; MTHFR; adjuvant chemotherapy;

    Sammanfattning : ABSTRACT Folates in the Treatment of Colorectal Cancer Department of Surgery Institute of Clinical Sciences at Sahlgrenska Academy University of Gothenburg Helena Taflin Background: Colorectal cancer is one of the most common cancers in the world, and radical surgery with total removal of the tumour (RO-resection) is the single most important treatment. However, chemotherapy is recommended for patients with risk factors and patients with metastatic disease. LÄS MER

  5. 19. Interactions between nutrition, obesity and the immune system

    Författare :Louise Strandberg; Göteborgs universitet; []
    Nyckelord :obesity; nutrition; infection; polymorphisms; interleukin; fatty acids; fat mass; neutrophils; innate immunity; mortality;

    Sammanfattning : There are several links between body fat and the immune system. For example, mice lacking activity of the pro-inflammatory interleukin-(IL)-1 and IL-6 develop obesity. Conversely, obesity is associated with adipose tissue inflammation and increased risk of infection. LÄS MER

  7. 20. Low CXCR1 Expression and Susceptibility to Acute Pyelonephritis

    Författare :Ann-Charlotte Lundstedt; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunology; mykologi; virology; mycology; Mikrobiologi; bakteriologi; virologi; Microbiology; bacteriology; Polymorphisms; Acute pyelonephritis; Chemokine receptor; serologi; Infections; Infektioner; Pediatrics; Pediatri; Immunologi;

    Sammanfattning : Urinary tract infections (UTIs) are clustered in certain individuals but the molecular basis of disease susceptibility is not known. A single gene was shown to control the susceptibility to acute pyelonephritis and renal scarring in mice. LÄS MER