Sökning: "Chemokine receptor"

Visar resultat 1 - 5 av 139 avhandlingar innehållade orden Chemokine receptor.

1. 1. Dysregulated mucosal immune responses in microscopic colitis patients

   Författare :Sezin Günaltay; Elisabeth Hultgren-Hörnquist; Olof Hultgren; Nils Nyhlin; Allan Mowat; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microscopic colitis; collagenous colitis; lymphocytic colitis; TLR; chemokine; chemokine receptor; IL-37; TCR; Immunologi; Immunology; Biomedicin; Biomedicine;

   Sammanfattning : Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC) is a common cause of chronic watery diarrhea. The diagnosis relies on typical histopathological changes observed upon microscopic examination. LÄS MER

3. 2. CXCL16 and CD137 in atherosclerosis

   Författare :Dick Wågsäter; Allan Sirsjö; Ewa Ehrenborg; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; atherosclerosis; chemokine; cytokine; endothelial cells; inflammation; low-density lipoprotein; macrophages; scavenger receptor; smooth muscle cells; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

   Sammanfattning : Atherosclerosis is a progressive inflammatory disease that is characterized by the accumulation of lipids, infiltrated cells and fibrous elements in large arteries. This thesis focuses on the molecular mechanisms behind foam cell formation and inflammation, two central processes in the development of atherosclerosis. LÄS MER

4. 3. Recruitment, Differentiation, and Function of monocytes during Salmonella infection

   Författare :Anna Rydström; Göteborgs universitet; []
   Nyckelord :Salmonella; Monocyte; Neutrophil; Chemokine; Toll-like receptor; Differentiation;

   Sammanfattning : Monocytes are a heterogeneous population in the blood with an enormous plasticity whose fate and functions are dictated by the microenvironment. They are phenotypically and functionally related to neutrophils and dendritic cells (DCs) and share an overlapping expression pattern of surface molecules with these cells. LÄS MER

5. 4. The G-protein coupled receptor CMKLR1/ChemR23: Studies on gene regulation, receptor ligand activation, and HIV/SIV co-receptor function

   Författare :Ulrika Mårtensson; Drug Target Discovery; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; HIV SIV; TIG2 chemerin; transcriptional regulation; ligand activation; Co-receptor; GPCR; ChemR23 CMKLR1;

   Sammanfattning : In all higher organisms, there is a need for intercellular communication. G-protein coupled receptors (GPCRs), located on the cell surface, play an important role in this communication. Cells synthesize and release signalling molecules (ligands), which produce a specific response only in those cells that have a receptor for that ligand. LÄS MER

7. 5. Chemokine receptor expression and function in experimental autoimmune neuroinflammation

   Författare :Sana Eltayeb; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Neuroinflammatory lesions in the central nervous system (CNS) are characterized by the presence of leukocytes, mainly monocytes/macrophages, derived from the systemic compartment. We believe CC inflammatory chemokine receptors (CkRs), CCR1, CCR2 and CCR5 are prerequisite for controlling the migration of monocytes/macrophages into inflammatory foci. LÄS MER