Sökning: "fragment impact"

Visar resultat 16 - 20 av 40 avhandlingar innehållade orden fragment impact.

1. 16. Filamin A in Cardiovascular Remodeling

   Författare :Sashidar Bandaru; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Filamin A; Cardiovascular remodelling;

   Sammanfattning : Filamin A (FLNA) is a large actin-binding cytoskeletal protein that stabilizes actin networks and integrates them with cell membranes. FLNA is therefore important for cell motility and organ development. LÄS MER

3. 17. Dissociative Recombination of Astrochemically Interesting Ions

   Författare :Mathias Hamberg; Wolf Geppert; Mats Larsson; Stephan Schlemmer; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dissociative Recombination; Astrochemistry; Chemical physics; Kemisk fysik; kemisk fysik; Chemical Physics;

   Sammanfattning : In this thesis the major work described concerns experimental determination of the dissociative recombination (DR) reaction for several molecular ions of astrochemical interest. DR is the process where an electron recombines with a molecular ion to form an excited neutral that disintegrates into two or more neutral fragments to release the gained excess energy. LÄS MER

4. 18. Neural networks in context: challenges and opportunities : a critical inquiry into prerequisites for user trust in decisions promoted by neural networks

   Författare :Lars Holmberg; Paul Davidsson; Per Linde; Carl Magnus Olsson; Maria Riveiro; Malmö universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Explainable AI; Machine Learning; Neural Network; Concept; Generalisation; Out-of-Distribution; Förklaringsbar AI; Maskininlärning; Neurala Nätverk; Koncept; Generalisering; Utanför-distributionen;

   Sammanfattning : Artificial intelligence and machine learning (ML) in particular increasingly impact human life by creating value from collected data. This assetisation affects all aspectsof human life, from choosing a significant other to recommending a product for us to consume. LÄS MER

5. 19. Use of microbiomics to study human impacts on complex microbial communities

   Författare :Cecilia Jernberg; Janet K. Jansson; Charlotta Edlund; Julian R. Marchesi; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The study of bacterial communities in nature is currently a challenge. The majority of bacteria in clinical and environmental samples have not yet been cultured and therefore we cannot fully understand their roles in nature and how the ecological balance in a specific microbial ecosystem can be disrupted. LÄS MER

7. 20. Novel Procedures for Identification and Characterization of Viral Proteases Inhibitors

   Författare :Angelica Ehrenberg; Helena Danielson; Celia Schiffer; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; drug discovery; viral proteases; inhibitors; Hepatitis C; NS3; cytomegalovirus; Biokemi; Biochemistry;

   Sammanfattning : Viral proteases are often considered to be attractive drug targets because of their crucial function in the viral replication machinery. In order to increase our knowledge of these important targets and to contribute to the discovery and development of new antiviral drugs, the proteases from hepatitis C virus (HCV) and human cytomegalovirus (HCMV) have been produced and their interactions with inhibitors and fragments have been characterized, using enzyme inhibition and SPR biosensor based interaction assay. LÄS MER