Sökning: "extra cellular matrix"

Visar resultat 1 - 5 av 34 avhandlingar innehållade orden extra cellular matrix.

  1. 1. Complex Formation in the Extra Cellular Matrix- Structural Study of CTLD of Agrrecan, Tenascin-R and Chondroadherin

    Författare :Anna Pramhed; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aggrecan; ECM; fibulin; structure; tenascin; CHAD; chondroadherin; X-ray; crystallography; calcium; CTLD; C-type lectin; fibronectin; FnIII; LRR; epidermal growth factor; leucine-rich repeat; matrix; EGF; cbEGF;

    Sammanfattning : The cells of higher organisms exist in a complex protein network, the extracellular matrix (ECM), which has a wide variety of different components such as glycoproteins, proteoglycans and carbohydrates. As well as being the physical scaffold on which the cells are dependent for their positioning and mobility, the ECM exercises control over the cells, and changes in the matrix will affect the adhesion, proliferation and differentiation properties of these cells. LÄS MER

  3. 2. Tumor instructed normal tissue : studies of potential extratumoral biomarkers and therapeutic targets in prostate cancer

    Författare :Maria Nilsson; Sofia Halin Bergström; Anders Bergh; Kristian Pietras; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; biomarkers; tumor-instructed normal tissue; extra cellular matrix; macrophages; LOX; HO-1; MSMB; Pathology; patologi;

    Sammanfattning : Prostate cancer is the most common cancer in men in Sweden and but luckily the majority of the patients will carry on their life without any consequences from the disease. Unfortunately, some will develop aggressive tumors and eventually die. LÄS MER

  4. 3. Regulation and function of mineralized tissue extra-cellular matrix proteins : studies of ADAMTS-1 and osteoadherin

    Författare :Anders Rehn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The extracellular matrix of tissues is governed and maintained by cells and a number of associated proteins. The extracellular matrix of the skeleton is highly specialized, in that it is mineralized and contains matrix-specific proteins with unique functions. LÄS MER

  5. 4. Collagen of the extracellular matrix. Functional and structural studies

    Författare :Olof Olsson; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Collagen; Extra Cellular Matrix. TGF-beta; integrin αvβ6;

    Sammanfattning : The cancer microenvironment has been attracting increasing attention as the realization of its importance for both disease treatment and malignant progression. Here the aim was to elucidate some of the effects and mechanisms of the tumor microenvironment related to the extracellular matrix (ECM). LÄS MER

  7. 5. Axon Guidance and Morphogenesis of the C. elegans Pharynx

    Författare :Manish Rauthan; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharynx; M2; C. elegans; extra-cellular matrix ECM ; hex; Krüppel; pha-2; isthmus; NSM; pharyngeal neurons.; cytoskeleton; mnm-2;

    Sammanfattning : The C. elegans pharynx is a single cell thick muscular tube that undergoes morphogenesis to attain it mature structure from a ball of 80 undifferentiated cells. This thesis is about understanding the mechanisms and the genetic pathways underlying the process of pharyngeogenesis. LÄS MER