Sökning: "early detection of recurrent breast cancer"

Hittade 3 avhandlingar innehållade orden early detection of recurrent breast cancer.

  1. 1. Molecular Analysis of Breast Cancer Transcriptomes, Genomes, and Circulating Tumor DNA

    Författare :Eleonor Olsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer stem cells; RNA splicing; breast cancer; mutations; circulating tumor DNA; early detection of recurrent breast cancer; sequencing;

    Sammanfattning : Breast cancer is a very heterogeneous disease in terms of clinical characteristics, genetic aberrations and prognosis. In Paper I, we focused on the CD44 molecule that often is aberrantly expressed in breast cancer and is widely used as a marker for cancer stem cells. LÄS MER

  2. 2. Colorectal cancer : genome, transcriptone and proteome dynamics

    Författare :Jens Karsten Habermann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Colorectal carcinomas are the third most common malignancies in the Western World. Despite screening programs about 70% of these tumors are detected at advanced stages. Late diagnosis, however, results in a significant reduction of average survival times. LÄS MER

  3. 3. Mitotic failure and genome stability in benign, premalignant and malignant human tissues

    Författare :Rüdiger G Steinbeck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :aneuploidy; CDF; clonal selection; DNA content; image microphotometry; interphase; microsection; nondisjunction; unbalanced telophase;

    Sammanfattning : Mitotic failure may occur throughout the human lifespan. Individual nuclear mistakes will escape detection within the mass of somatic cells. The probability of nondetection increases with progression in development. LÄS MER