Sökning: "circulating tumor DNA"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden circulating tumor DNA.
1. Circulating platelets : a novel liquid biopsy source for cancer diagnostics and therapy stratification
Sammanfattning : As conventional tissue biopsies have several drawbacks, much effort has been directed toward the development of minimal-invasive liquid biopsy platforms for detecting and profiling cancer.Platelets are the second most abundant cells in blood and have very versatile functions both in physiological and pathophysiological conditions. LÄS MER
2. Molecular Analysis of Breast Cancer Transcriptomes, Genomes, and Circulating Tumor DNA
Sammanfattning : Breast cancer is a very heterogeneous disease in terms of clinical characteristics, genetic aberrations and prognosis. In Paper I, we focused on the CD44 molecule that often is aberrantly expressed in breast cancer and is widely used as a marker for cancer stem cells. LÄS MER
3. Next generation molecular diagnostics using ultrasensitive sequencing
Sammanfattning : Massively parallel sequencing enables the exploration of the genetic heterogeneity within microbial, viral and tumor cell populations. Detecting circulating tumor DNA in blood and other body fluids has the potential to revolutionize molecular diagnostics. LÄS MER
4. Circulating markers of risk and etiology in colorectal cancer
Sammanfattning : Background: Colorectal cancer is the third most commonly diagnosed cancer in men and women. Worldwide around 2 million individuals are diagnosed each year – a number expected to increase as colorectal cancer risk factors become more prevalent. LÄS MER
5. Methods for deep examination of DNA
Sammanfattning : The development of sequencing technology has had a rapid pace during the last years and today, the sequencing instruments harbors enormous capacity. This thesis is about the development of methods to make the most out of this capacity and to use it for various applications. LÄS MER