Sökning: "dioxin"

Visar resultat 21 - 25 av 85 avhandlingar innehållade ordet dioxin.

  1. 21. Health risk assessment of dioxin-like compounds in complex samples

    Författare :Mattias U L Öberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : There are several scientific as well as political and economic reasons why the risk assessment of dioxins in complex samples needs to be further refined. Today, there seems to be no margin of safety between doses that cause suspected effects and exposure. Therefore, uncertainties and gaps in the knowledge have to be minimized. LÄS MER

  3. 22. Dioxins and dioxin-like compounds in thermochemical conversion of biomass : formation, distribution and fingerprints

    Författare :Qiuju Gao; Stina Jansson; Bogdan Dlugogorski; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Polychlorinated dibenzo-p-dioxins; polychlorinated dibenzofurans; polychlorinated naphthalenes; PCDD; PCDF; PCN; persistent organic pollutants; torrefaction; pyrolysis;

    Sammanfattning : In the transition to a sustainable energy supply there is an increasing need to use biomass for replacement of fossil fuel. A key challenge is to utilize biomass conversion technologies in an environmentally sound manner. LÄS MER

  4. 23. Regulation of dioxin receptor activity by phosphorylation and protein-protein interaction

    Författare :Ingemar Pongratz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The dioxin receptor together with its partner factor Arnt belongs to the basic helix-loop-helix/PAS family of transcription factors. The receptor is the mediator of the biological effects of a number of environmental pollutants such as dioxin and other related compounds. LÄS MER

  5. 24. Functional role of a constitutively active dioxin/Ah receptor in a transgenic mouse model

    Författare :Patrik Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dioxin Ah receptor; TCDD; dioxin; stomach tumor; osteopontin; peritoneal B1 B cells; transcription factor; gene expression;

    Sammanfattning : The dioxin/ Aryl hydrocarbon receptor is a ligand-activated transcription factor that mediates most (if not all) of the toxic effects of the group of highly potent environmental pollutants collectively called dioxins and PCBs, including the highly toxic compound 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD). The toxic effects include immune suppression, endocrine disruption, impaired reproduction and carcinogenesis. LÄS MER

  7. 25. Inducible and constitutive modes of gene regulation by the dioxin receptor and Arnt

    Författare :Camilla Antonsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Heterodimeric complexes between the basic helix-loop-helix (bHLH)/PAS (Per-Arnt-Sim) transcription factors, dioxin receptor and Arnt, are involved in mediating cellular responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin). The unliganded dioxin receptor is found in the cytoplasm complexed with the 90-kDa heat shock protein hsp90, in a latent inactive (non-DNA binding) configuration. LÄS MER