Sökning: "cholinergic system"

Visar resultat 16 - 20 av 94 avhandlingar innehållade orden cholinergic system.

  1. 16. Effects of sevoflurane anesthesia on cognitive function and cholinergic signaling

    Författare :Andreas Wiklund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Postoperative cognitive dysfunction;

    Sammanfattning : In recent years, concerns have been raised regarding the potential negative impact of anesthetic drugs in postoperative cognitive dysfunction. This thesis is an attempt to contribute to the understanding of the underlying mechanisms. LÄS MER

  3. 17. Pamoplantar Pustulosis. Pathogenetic Studies with Special Reference to the Role of Nicotine

    Författare :Eva Hagforsen; Uppsala universitet; []
    Nyckelord :Medical sciences; Palmoplantar pustulosis; smoking; sweat gland apparatus; neuropeptides; non-neuronal cholinergic system; nicotinic receptor antibodies; autoimmune disease; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

    Sammanfattning : Palmoplantar pustulosis (PPP) is a chronic disease of unknown pathogenesis. Most of the patients were smokers. High prevalence of a number of autoimmune diseases was observed among the patients (thyroid disease 14%, gluten intolerance 8%, diabetes type 1 3%). Eosinophils and neutrophils were found in large numbers in the pustules. LÄS MER

  4. 18. Neuronal types and their specification dynamics in the autonomic nervous system

    Författare :Alessandro Furlan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The autonomic nervous system is formed by a sympathetic and a parasympathetic division that have complementary roles in the maintenance of body homeostasis. Autonomic neurons, also known as visceral motor neurons, are tonically active and innervate virtually every organ in our body. LÄS MER

  5. 19. Implantable bioartificial hybrids for targeted therapy in the central nervous system

    Författare :Lars U Wahlberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The rapid increase in the understanding of the CNS at the molecular level has brought us new knowledge and tools to attempt to locally manipulate the CNS microenvironment and thereby introduce reparative and ablative molecular therapeutic approaches in focal areas of the CNS. This targeted therapy will require neurosurgical intervention for the injection and implantation of cells, viral vectors, or drug release systems. LÄS MER

  7. 20. On age related changes in axons and glia of the central nervous system

    Författare :Susanna Kullberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aging; synaptic input; spinal cord; hippocampus; amino acid neurotransmitters; astrocyte; microglia; oligodendroglia; C bouton; cholinergic; monoaminergic; cytokine;

    Sammanfattning : A growing body of evidence shows that phenotypic changes including axon aberrations, rather than loss of neurons, account for behavioral impairments during aging. The present thesis was undertaken to investigate the occurrence of axon aberrations in relation to transmitter identity, glial reaction and sensorimotor disturbances. LÄS MER