Sökning: "cholinergic system"
Visar resultat 11 - 15 av 94 avhandlingar innehållade orden cholinergic system.
11. Retention and effects of some chlorinated hydrocarbons in the brain of the postnatal mouse : exposure during a period of rapid development of the cholinergic system in the brain
Sammanfattning : .... LÄS MER
12. Modeling disturbances of cholinergic systems : possible relevance for schizophrenia
Sammanfattning : Schizophrenia is a severe, chronic mental disorder. The etiology remains unknown but alterations in cholinergic neurotransmission is one, among other, disturbances in the brain that have been implicated in schizophrenia. LÄS MER
13. The hippocampal opioid system : role in spatial learning
Sammanfattning : The main aim of the present thesis was to study the role of the endogenous hippocampal opioid system, and in particular, the role of dynorphin B and nociceptin, in spatial learning. The effects of bilateral infusion (using chronic cannulae) of dynorphin B into the dorsal hippocampus (CA3-region), an area containing a high number of dynorphin-containing neurons, were examined in the Morris swim-maze, a spatial task dependent on hippocampal functioning. LÄS MER
14. Apolipoprotein E and cholinergic enzymes : the interface in dementia
Sammanfattning : The main confirmed genetic risk factor for sporadic form of Alzheimer’s disease (AD) is apolipoprotein E (ApoE) ε4 allele (APOE4). ApoE protein aids in receptor ligand mediated transport, distribution and metabolism of fatty acids and cholesterol. LÄS MER
15. Pharmacological and environmental modulations of the rat glutamatergic system
Sammanfattning : Glutamate is the principal excitatory neurotransmitter in the central nervous system and it is implicated in neural transmission, learning, memory processes and neuronal plasticity. In the glutamatergic synapse two main components are present; the glutamate receptors and the glutamate transporters. LÄS MER
