Sökning: "cellular retinol-binding protein"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden cellular retinol-binding protein.

  1. 1. Disruption of vitamin A metabolism by dioxin

    Författare :Pi Högberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :TCDD; dioxin; vitamin A; retinoic acid; cellular retinol-binding protein; bone;

    Sammanfattning : Vitamin A (retinoids) is a nutrient that plays a central role in development and remains essential for cell growth and differentiation throughout life. Dioxins are polychlorinated organic pollutants known to negatively affect the storage and body clearance of retinoids. LÄS MER

  3. 2. Studies on the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on vitamin A homeostasis

    Författare :Charlotte Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :TCDD; dioxin; vitamin A; retinoic acid; lecithin:retinol acyltransferase; retinyl ester hydrolysis; retinol-binding protein; kidney; lymph; stellate cell; kinetics; model-based compartmental analysis;

    Sammanfattning : Vitamin A (retinoids) is needed for normal vision, growth, reproduction, cell differentiation, embryonic development, and immune function. Retinoids exert their functions in the same way as classical hormones, as transcription factors acting via nuclear receptors. LÄS MER

  4. 3. Structural aspects of binding and transport proteins : By Barnali Neel Chaudhuri

    Författare :Barnali Neel Chaudhuri; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Binding and transport proteins are essential for the transport of nutrients, vitamins, hormones, pheromones, etc. to their target destinations. Lipid-binding proteins typically contain an internal cavity where the hydrophobic/amphipathic ligands bind. Transport proteins with binding clefts for water-soluble sugars have different architectures. LÄS MER

  5. 4. Molecular Aspects of Transthyretin Amyloid Disease

    Författare :Karin Sörgjerd; Per Hammarström; Joel Buxbaum; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid; apoptosis; BiP; chaperone; misfolding; oligomer; transthyretin; Biochemistry; Biokemi;

    Sammanfattning : This thesis was made to get a deeper understanding of how chaperones interact with unstable, aggregation prone, misfolded proteins involved in human disease. Over the last two decades, there has been much focus on misfolding diseases within the fields of biochemistry and molecular biotechnology research. LÄS MER

  7. 5. Retinoids and vitamin D in skin and parathyroid glands

    Författare :Liu Wei; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; all-trans retinoic acid 9-cis retinoic acid vitamin A. vitamin D. CRBP. CRABP. RAR. RXR. parathyroid hormone. calcium receptor; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Vitamin D3 (VitD3) and retinoids are important factors involved in differentiation and proliferation in many cell systems. Their effects in skin, where retinoids and vitamin D are known to be crucially involved in keratinocyte differentiation and function,, and in the parathyroid, the overall regulatory organ in calcium homeostasis were studied. LÄS MER