Sökning: "cell-cell interactions"

Visar resultat 6 - 10 av 76 avhandlingar innehållade orden cell-cell interactions.

  1. 6. Nephrin cellular trafficking and intracellular interactions

    Författare :Xiao Li Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nephrin; signal; missense mutations; trafficking.;

    Sammanfattning : Nephrin is a 180-kDa transmembrane glycoprotein belonging to the immunoglobulin family of cell adhesion molecules. Nephrin has an extracellular part with eight Ig-like motifs, one fibronectin-like domain, a transmembrane region and a short cytoplasmic tail. LÄS MER

  3. 7. Virus Host Interactions in SARS Coronavirus Infection

    Författare :Vithiagaran Gunalan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The global outbreak of Severe Acute Respiratory Syndrome which began in 2002 and ended in 2003 resulted in over 8000 cases in 29 countries, causing an atypical pneumonia which resulted in a case fatality rate of ~10%. The etiological agent of this disease was found to be a novel coronavirus dubbed SARS Coronavirus (SARS-CoV). LÄS MER

  4. 8. Protein Dimensions and Interactions at Immune-Cell Contacts

    Författare :Victoria Junghans; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Immune cells, such as B and T cells, fight pathogens infecting the human body. To fulfil this function the immune cells need to form a contact during which different membrane proteins play an important role. LÄS MER

  5. 9. Structure and energetics of molecular recognition in galectin-3-ligand interactions

    Författare :Rohit Kumar; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein-ligand interactions; molecular recognition; weak bonds; thermodynamics; enthalpy; entropy; galectin-3; carbohydrate recognition domain; x-ray crystallography; fluorescence polarization; isothermal titration calorimetry; neutron crystallography; ;

    Sammanfattning : Molecular recognition is the key aspect of any cellular and biological function. Two or more molecules interacting with each other cause the effects that drives various basic functions that are fundamental to cells. Be these protein-protein, protein-nucleic acid or protein-ligand interactions, they all play important roles in a cell. LÄS MER

  7. 10. Cell interactions in the CNS and their consequences for neuronal apoptosis

    Författare :Mikaela Berglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aggregate cultures; apoptosis; automated image analysis; cytochrome c; interactions; JNK; microglia; neuron; neural precursor cells; rotenone; UV.;

    Sammanfattning : The central nervous system consists of an intricate network of neurons and glial cells that depend on reciprocal communication to develop and maintain the vital functions of the brain. if the balance is disturbed by injury or disease, two cell types in particular, microglia and astrocytes, respond by producing factors that help combat the infection or delimit the affected area. LÄS MER