Sökning: "breast cancer metastases"

Visar resultat 1 - 5 av 67 avhandlingar innehållade orden breast cancer metastases.

  1. 1. Type IV collagen in breast and colorectal cancer : a potential biomarker of metastatic disease

    Författare :Moa Lindgren; Hanna Nyström; Ingrid Ljuslinder; Malin Sund; Kristian Pietras; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; breast cancer; breast cancer metastases; tumor marker; biomarker; stroma; type IV collagen;

    Sammanfattning : Background: Metastatic colorectal cancer (mCRC) and metastatic breast cancer (mBC) are two leading causes of cancer-related mortality worldwide. Early detection of metastatic disease is critical, and sensitive, easily accessed and cost-effective biomarkers that can diagnose mBC and mCRC at an early stage would have high clinical value. LÄS MER

  3. 2. Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer

    Författare :Sara Alkner; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; prognosis; treatment prediction; endocrine treatment; tamoxifen; coactivator; AIB1; PAX2; SRC; contralateral breast cancer; premenopausal; randomized trial; mode of detection; mammography.;

    Sammanfattning : One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. LÄS MER

  4. 3. Studies on Prediction of Axillary Lymph Node Status in Invasive Breast Cancer

    Författare :Johan Ahlgren; Karl von Smitten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Breast cancer; lymph node metastases; prognostic factors; predictive factors; axillary surgery; angiogenesis; immunohistochemistry; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : Breast cancer is the most common malignancy among females in Sweden. Axillary lymph-node dissection is a standard procedure in the management of breast cancer, aiming at obtaining prognostic information for adjuvant therapy decisions. Axillary dissection entails considerable morbidity. LÄS MER

  5. 4. Individually Tailored Toxicity-based Chemotherapy : Studies on Patients with Primary and Metastatic Breast Cancer

    Författare :Henrik Lindman; Jonas Bergh; Carl Blomqvist; Peter Nygren; Bo Nordenskjöld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; breast cancer; tailored chemotherapy; toxicity-based dosing; high-dose therapy; MR imaging; G-CSF; epirubicin; docetaxel; cyclophosphamide; 5-fluorouracil; Onkologi; Oncology; Onkologi;

    Sammanfattning : Standard dosing of chemotherapy based on body surface area (BSA) results in large individual differences in toxicity due to a large inter-patient variability in pharmacokinetics (PK) and pharmacodynamics (PD). This results in under-dosing in certain patients with a potentially weaker antitumoral effect. LÄS MER

  7. 5. Cytogenetic studies of primary and metastatic breast cancer

    Författare :Adewale Adeyinka; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; histokemi; cytokemi; Histologi; tissue culture; cytochemistry; histochemistry; Histology; metastases; prognosis; male breast cancer; breast cancer; trisomy 12; Cytogenetics; chromosomes; vävnadskultur; Clinical genetics; Klinisk genetik;

    Sammanfattning : A series of primary and metastatic breast carcinomas obtained from female and male patients were cytogenetically analysed. Trisomy 12 was identified as a recurrent and sometimes early event in breast carcinogenesis. LÄS MER