Sökning: "autoxidation"

Visar resultat 6 - 10 av 16 avhandlingar innehållade ordet autoxidation.

  1. 6. Formation of Skin Sensitizers from Fragrance Terpenes via Oxidative Activation Routes. Chemical analysis, Structure Elucidation and Experimental Sensitization Studies

    Författare :Lina Hagvall; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The work presented in this thesis emphasizes the importance of considering oxidative activation in the toxicity assessment of fragrance chemicals. Compounds without contact allergenic properties can be activated either via autoxidation in contact with air or via cutaneous metabolism to reactive products which can cause contact allergy. LÄS MER

  3. 7. Biotransformations of Turpentine Constituents : Oxygenation and Esterification

    Författare :Marica Lindmark-Henriksson; KTH; []
    Nyckelord :Picea abies; Pinaceae; Essential oils composition; Terpene alcohol; Hemiacetal; Hemiacetal ester; TMP-turpentine; Monoterpene; alpha-pinene; beta-pinene; Limonene; Verbenol; Pinocarveol; Borneol; Myrtenol; Suspension cell culture; Biotransformation; ;

    Sammanfattning : This thesis describes methods to obtain value–addedcompounds from TMP-turpentine obtained from the spruce, Piceaabies. The methodology focuses on biotransformations using twoapproaches: an oxygenation approach (i.e. oxygenation ofterpene hydrocarbons by cell cultures) and an esterificationapproach (i. LÄS MER

  4. 8. Exploring Novel Catalytic Chalcogenide Antioxidants

    Författare :Henrik Johansson; Lars Engman; Helena Grennberg; Troels Skrydstrup; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antioxidant; tellurium; selenium; catalytic; toxicity; ROS; neutrophil; glutathione peroxidase mimic; macrophage.; Organic chemistry; Organisk kemi; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

    Sammanfattning : This thesis is concerned with the synthesis and evaluation of regenerable chalcogen containing antioxidants. Variously substituted 2,3-dihydrobenzo[b]selenophene-5-ol antioxidants were evaluated in order to gain information about structure/reactivity-relationships. LÄS MER

  5. 9. Allergenic oxidation products in ethoxylated non-ionic surfactants : Chemical characterization and studies on allergenic activity

    Författare :Margareta Bergh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Sammanfattning : The susceptibility of ethoxylated non-ionic surfactants to oxidation on exposure to air was investigated. Surfactants have a complex chemical composition and are widely used in a variety of applications for to their amphiphilic properties. Ethoxylated non-ionic surfactants are regarded by the producers to be stable at normal handling. LÄS MER

  7. 10. Mass Spectrometric Analysis of Oxylipins : Application to Cytochrome P450-Dependent Metabolism

    Författare :Tomas Nilsson; Ernst Oliw; Johan Bylund; Mikael Hedeland; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epoxyalcohols; fatty acids; hydroperoxides; electrospray ionization; ichthyosis; CYP4; linear ion trap; fragmentation mechanism; Pharmaceutical pharmacology; Farmaceutisk farmakologi; Biochemical Pharmacology; Biokemisk farmakologi;

    Sammanfattning : Cytochrome P450 (CYP) family 4 constitutes monoxygenases responsible for hydroxylation of fatty acids and other lipids. For example, CYP4F3 metabolizes leukotrienes and CYP4F8 prostaglandin H. Importantly, six of the twelve CYP4 enzymes are orphans, i.e. LÄS MER