Sökning: "Thomas Höglund"

Hittade 5 avhandlingar innehållade orden Thomas Höglund.

  1. 1. Regulation of DNA damage responses by the Myc oncogene : implications for future anti-cancer therapies

    Författare :Andreas Höglund; Jonas Nilsson; Thomas Helleday; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Myc; DNA damage; Decitabine; Chk1; Chk2; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Myc is a transcription factor frequently found deregulated in human cancer. Cells with deregulated expression of Myc carry a selective advantage against its neighbours due to the fact that Myc-mediated transcription governs crucial cellular events such as proliferation and growth. LÄS MER

  2. 2. Violence in the Midst of Peace Negotiations : Cases from Guatemala, Northern Ireland, South Africa and Sri Lanka

    Författare :Kristine Höglund; Thomas Ohlson; Mats Hammarström; Roy Licklider; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Peace and conflict research; conflict resolution; internal conflict; violence; peace process; negotiation; Guatemala; Northern Ireland; South Africa; Sri Lanka; Freds- och konfliktforskning; Peace and conflict research; Freds- och konfliktforskning; Peace and Conflict Research; freds- och konfliktforskning;

    Sammanfattning : Why do peace talks fall apart as a result of violence? The present study addresses the question of why and how violence sometimes changes the dynamics of peace negotiation processes. Incidents of violence may produce friction between and within parties. LÄS MER

  3. 3. Dangerous Liaisons : Why Ex-Combatants Return to Violence. Cases from the Republic of Congo and Sierra Leone

    Författare :R. Anders Nilsson; Thomas Ohlson; Kristine Höglund; Mats Hammarström; Joanna Spear; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; ex-combatants; reintegration; demobilization; DDR; conflict resolution; peacebuilding; civil wars; Republic of Congo; Sierra Leone; Peace and conflict research; Freds- och konfliktforskning;

    Sammanfattning : After disarming and demobilizing, why do some ex-combatants re-engage in organized vio-lence, while others do not? Even though former fighters have been identified as a major source of insecurity in post-civil war societies due to their military know-how, there have been few efforts to systematically examine this puzzle. This study fills this research gap by comparing the presence or absence of organized violence in different ex-combatant communi-ties – all the former fighters that used to belong to the same armed faction and who share a common, horizontal identity based on shared war-and peacetime experiences. LÄS MER

  4. 4. Markov Chains, Renewal, Branching and Coalescent Processes : Four Topics in Probability Theory

    Författare :Andreas Nordvall Lagerås; Thomas Höglund; Ingemar Kaj; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mathematical statistics; Matematisk statistik; matematisk statistik; Mathematical Statistics;

    Sammanfattning : This thesis consists of four papers.In paper 1, we prove central limit theorems for Markov chains under (local) contraction conditions. As a corollary we obtain a central limit theorem for Markov chains associated with iterated function systems with contractive maps and place-dependent Dini-continuous probabilities. LÄS MER

  5. 5. Vetenskapens verklighet : Om motsättningen mellan realism och konstruktivism i vetenskapsfilosofin

    Författare :Eva Boo Höglund; Fredrik Stjernberg; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Theoretical philosophy; constructivism; realism; scientific theory; world; reality; language; Kuhn; Boyd; Teoretisk filosofi; Theoretical philosophy; Teoretisk filosofi; teoretisk filosofi; Theoretical Philosophy;

    Sammanfattning : This thesis investigates the conflict between a constructivist and a realist understanding of scientific theories. It focuses on the constructivism formulated by Thomas S. Kuhn and the realism formulated by Richard Boyd, but also relates these conceptions to other forms of constructivism and realism described in the literature. LÄS MER