Sökning: "Shb"
Visar resultat 16 - 18 av 18 avhandlingar innehållade ordet Shb.
16. Signal transduction pathways involved in PDGF receptor-induced cellular responses
Sammanfattning : Platelet-derived growth factor (PDGF), is a potent connective tissue cell mitogen and chemoattractant which binds to two structurally related receptors denoted PDGF α- and β- receptors. Upon binding of PDGF to the receptor, signaling molecules containing Src Homology 2 (SH2) domains are recruited to the activated receptor and mediate propagation of the signal. LÄS MER
17. Anti-Diabetic and Beta-Cell Protective Actions of Imatinib Mesylate
Sammanfattning : Type 1 diabetes is a disease resulting from the progressive immune-mediated destruction of insulin producing β-cells. In order to understand more about diabetes we need to understand the mechanisms governing β-cell death.The leukemia drug Gleevec is a tyrosine kinase inhibitor that targets c-Abl. LÄS MER
18. Endothelial differentiation and angiogenesis regulation
Sammanfattning : Angiogenesis can be defined as the formation of new blood vessels from pre-existing ones. Angiogenesis is required for development and maintenance of our vascular system and thus of fundamental importance to our existence. LÄS MER
