Sökning: "RhoD"

Hittade 3 avhandlingar innehållade ordet RhoD.

1. 1. Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

   Författare :Johan Heldin; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; cell migration; signaling; VEGF; FGD5; ExoC3L2; microRNA; RhoD; Molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : Blood vessels deliver nutrients and oxygen to tissues. Importantly, the functions and growth of blood vessels are commonly altered in disease. The inside of all blood vessels are lined with endothelium, a thin specialized layer of endothelial cells that separate the blood from other tissues. LÄS MER

3. 2. The atypical Rho GTPase RhoD and its role in cellular dynamics

   Författare :Magdalena Blom; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Despite its discovery 20 years ago, the accumulated knowledge about the Rho member RhoD is scarce. Instead, the vast majority of studies concerning Rho GTPases has focused on the three classical members RhoA, Cdc42 and Rac1. In contrast, RhoD is considered an atypical Rho GTPase, with an aberrant GTP/GDP cycling and an unknown regulation. LÄS MER

4. 3. The role of RhoD in actin dynamics, receptor trafficking and cancer cell migration

   Författare :Vishal Nehru; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The Ras subfamily of Rho GTPases plays an important role in myriads of cell processes, such as actin cytoskeleton dynamics, membrane trafficking and cell migration. Additionally, they also participate in diverse signal transduction pathways that regulate gene transcription, cell survival and cell growth. LÄS MER