Sökning: "Phosphopeptides"
Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet Phosphopeptides.
1. New fractionation tools targeting elusive post-translational modifications
Sammanfattning : Protein phosphorylation is a reversible post-translational modification (PTM)playing a central role in numerous biological events including disease pathogenesis.Thus, the analysis of phosphoproteome is crucial for understandingcellular regulation processes and can facilitate the development of new diagnosticand therapeutic tools. LÄS MER
2. Phosphoproteomic analysis of Arabidopsis thaliana ribosomes
Sammanfattning : Ribosomes serve as the site of protein synthesis in all living cells. Ribosomes were discovered in 1955 by George E. Palade when he was studying the endoplasmic reticulum which is covered by ribosomes. He received the Nobel Prize in Physiology or Medicine in 1974 for this discovery. LÄS MER
3. Sample preparation and mass spectrometry in proteome studies
Sammanfattning : Proteome studies aim to link gene to function. Instead of screening for function in a specific protein as in classical protein chemistry, proteins are now screened against a specific phenotype, disease or metabolic state. LÄS MER
4. Proteomic analyses of bioactive molecules in health and disease
Sammanfattning : After the mapping of genomes and knowing the blueprints of the possible gene products, focus is shifting from genomics to proteomics. Proteome analyses can be used for diagnosis, prognosis and monitoring of diseases and for characterization of bioactive compounds and their mechanisms of action. LÄS MER
5. POROUS POLYMERS AND DESIGNED SORBENTS FOR APPLICATIONS IN BIOMEDICAL RESEARCH
Sammanfattning : Everyday millions of bioanalyses are performed in clinical laboratories, hospitals and research centers, where technicians and bio-analysts utilize analytical chemistry principles and instruments to serve medicine and biomedical research. A method routinely used for sample preparation in bioanalysis is solid-phase extraction (SPE). LÄS MER