Sökning: "Phosphohistidine"

Hittade 2 avhandlingar innehållade ordet Phosphohistidine.

1. 1. New fractionation tools targeting elusive post-translational modifications

   Författare :Celina Wierzbicka; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular imprinting; Molecular recognition; Phosphopeptides; Proteomics; Phosphotyrosine; Phosphohistidine;

   Sammanfattning : Protein phosphorylation is a reversible post-translational modification (PTM)playing a central role in numerous biological events including disease pathogenesis.Thus, the analysis of phosphoproteome is crucial for understandingcellular regulation processes and can facilitate the development of new diagnosticand therapeutic tools. LÄS MER

3. 2. Studies on Phosphohistidine Phosphatase 1 : What? Where? Why?

   Författare :Ulla Beckman Sundh; Pia Ek; Örjan Zetterqvist; Jin-ping Li; Christian Hedberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHPT1; Phosphohistidine phosphatase; PHP; Assay; Medical Biochemistry; Medicinsk biokemi;

   Sammanfattning : Phosphohistidine phosphatase 1 (PHPT1) is a small protein, consisting of 125 amino acids, that catalyzes the dephosphorylation of histidine but does not have any activity towards other phosphorylated amino acids. PHPT1 was identified in 2002, and is so far the only mammalian histidine phosphatase known, but still little is known about its physiological role. LÄS MER