Sökning: "Per Sandström"

Visar resultat 16 - 20 av 24 avhandlingar innehållade orden Per Sandström.

1. 16. Peptidomimetic Enzyme Inhibitors : Targeting M. tuberculosis Ribonucleotide Reductase and Hepatitis C Virus NS3 Protease

   Författare :Johanna Nurbo; Anders Hallberg; Anders Karlén; Anja Sandström; Per Arvidsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzyme inhibitor; peptidomimetics; structure-activity relationship; tuberculosis; ribonucleotide reductase; hepatitis C virus; NS3 protease; Pharmaceutical chemistry; Farmaceutisk kemi; Medicinal Chemistry; Läkemedelskemi;

   Sammanfattning : This thesis focuses on the design and synthesis of inhibitors targeting Mycobacterium tuberculosis ribonucleotide reductase (RNR) and hepatitis C virus (HCV) NS3 protease; enzymes that have been identified as potential drug targets for the treatment of tuberculosis and hepatitis C, respectively. Small peptides have been recognized as inhibitors of these enzymes. LÄS MER

3. 17. Stromal collagens in colorectal cancer and in colorectal liver metastases : tumour biological implications and a source for novel tumour markers

   Författare :Hanna Nyström; Malin Sund; Peter Naredi; Per Sandström; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; tumour marker; stroma; type IV collagen; metastatic growth pattern; kirurgi; Surgery;

   Sammanfattning : Background: Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality. About 50 % of patients with CRC will develop subsequent liver metastases (CLM). The survival for untreated CLM is only a few months and liver resection provides the only chance for a lasting cure. LÄS MER

4. 18. Modifying kraft pulping to produce a softwood pulp requiring less energy in tissue paper production

   Författare :Hafizur Rahman; Per Engstrand; Mikael E. Lindström; Louise Logenius; Peter Sandström; Ulf Germgård; Mittuniversitetet; []
   Nyckelord :Modifying kraft pulp; tissue dewatering; polysulfide; sodium borohydride; tensile index; hemicellulose;

   Sammanfattning : Modification of softwood kraft pulp by the addition of either polysulfide (PS) or sodium borohydride (NaBH4) has been shown to increase the pulp yield due to a higher retention of glucomannan.  The pulps with higher yield gave a paper with higher tensile index than reference pulp, especially at lower degrees of refining. LÄS MER

5. 19. Three faces of HELCOM - institution, organization, policy producer

   Författare :Matilda Valman; Andreas Duit; Henrik Österblom; Per Olsson; Urika Mörth; Annica Sandström; Stockholms universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Helsinki Commission; institutional change; policy change; organizational response; ecosystem approach; Baltic Sea; BSAP; content analysis; Political Science; statsvetenskap;

   Sammanfattning : Despite early initiatives during the 1960s and 1970s, and continuing efforts ever since, the Baltic Sea remains in poor condition. The Helsinki Commission (HELCOM) is the governing body tasked with protecting the marine environment from further deterioration through intergovernmental collaboration between the Baltic Sea states and the EU. LÄS MER

7. 20. Essays on Saving, Borrowing and Intangible Capital

   Författare :Maria Sandström; Nils Gottfries; Johan Lyhagen; Torben Mideksa; David Domeij; Uppsala universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Intangible Capital; Markups; Economic Profit; Household Savings; Pension Reform; Heterogeneous Agents; Monetary Policy Shocks; Economics; Nationalekonomi;

   Sammanfattning : Essay I: Can an increasing importance of intangible capital in the economy explain increases in markups and profits? I use a heterogeneous firm model to show how intangible capital is related to markups and profits at the industry level. The uncertainty and scalability properties of intangible capital imply that firms that succeed in their intangible capital investment can charge high markups relative to other firms, whereas firms that fail will exit. LÄS MER