Sökning: "Nils Hansen"

Hittade 1 avhandling innehållade orden Nils Hansen.

1. 1. Functional Modeling of Genes Upregulated in Chronic Myeloid Leukemia

   Författare :Nils Hansen; Avdelningen för klinisk genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic myeloid leukemia; SOCS2; IL1RAP; BCR ABL1; leukemia models;

   Sammanfattning : Chronic myeloid leukemia (CML) is caused by the transformation of a primitive hematopoietic cell by the BCR/ABL1 fusion gene that is formed through the chromosomal translocation t(9;22). CML is currently successfully treated with tyrosine kinase inhibitors targeting the ABL1 kinase domain. LÄS MER