Sökning: "Mikael Brink"
Hittade 4 avhandlingar innehållade orden Mikael Brink.
1. Presence of immunological markers preceding the onset of rheumatoid arthritis
Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease with an unknown aetiology characterized by joint destruction. Both genetic and environmental factors contribute to the disease development with HLA-DRB1* alleles and smoking identified as most important. LÄS MER
2. Early rheumatoid arthritis : biomarkers and hormonal factors in relation to disease progression
Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, affecting approximately 0.5 to 1% of the adult population. Although the aetiology is not fully known, a complex interaction between genetic, environmental and stochastic factors is thought to trigger the pathogenic mechanisms. LÄS MER
3. Insights into the processes preceding the onset of rheumatoid arthritis
Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by the production of anti-citrullinated protein antibodies (ACPA) in the majority of all patients and a persistent inflammation in the synovial tissue leading to joint destruction. The aetiology of RA remains to a large extent unknown but is believed to be a complex interplay between genetic, environmental and stochastic factors. LÄS MER
4. Population size and genetic diversity of Nigerian lions (Panthera leo)
Sammanfattning : High growth rate in human populations, agricultural developments and industrialization have impinged negatively on the natural habitats of most large carnivores, causing fragmentation, isolation and consequently reduction in population size. Lions (Panthera leo) that once roamed most parts of Southern Europe, Asia, the Middle East, North America, northern part of South America and most parts of Africa are today found only in parts of sub-Saharan Africa and at a single site in India. LÄS MER