Sökning: "K May"

Visar resultat 1 - 5 av 818 avhandlingar innehållade orden K May.

  1. 1. Improved dose response modeling for normal tissue damage and therapy optimization

    Författare :Magdalena Adamus-Górka; Bengt K. Lind; Anders Brahme; Panayiotis Mavroidis; Randall K. Ten Haken; Stockholms universitet; []
    Nyckelord :Normal tissue complications; radiobiological models; dose-response; volume effect; spinal cord; effective FSU size; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : The present thesis is focused on the development and application of dose response models for radiation therapy. Radiobiological models of tissue response to radiation are an integral part of the radiotherapeutic process and a powerful tool to optimize tumor control and minimize damage to healthy tissues for use in clinical trials. LÄS MER

  3. 2. Structural pathology and functional analysis of vitamin K-dependent protein S

    Författare :Tusar K Giri; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C4b-binding protein; Protein S; blood coagulation; thrombosis; natural mutations; in vitro characterization.; Immunology; transplantation; serologi; Immunologi; serology;

    Sammanfattning : Protein S deficiency is an autosomal dominant trait affecting around 10% of families thrombophilic families. The high affinity interaction of approximately 60% of protein S with C4b -binding protein (C4BP) has raised a complicated situation for the diagnosis of deficiency states. LÄS MER

  4. 3. Translational perspectives on MSMB and CRISP3 expression and regulation in prostate cancer

    Författare :Anna K Dahlman; Malmö Urologisk cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Prostate cancer is currently the most common form of cancer in Sweden. Currently, the only biomarker used in the clinic is serum PSA, and there is a great need for new biomarkers that may increase the diagnostic and prognostic information so that better predictions can be made, and treatment may be tailored. LÄS MER

  5. 4. Dynamic magnetic resonance imaging of the breast : imaging features for diagnosis and prognosis of breast cancer

    Författare :Botond K Szabo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast neoplasm; magnetic resonance imaging; prognostic factors; survival analysis; image segmentation; artificial neural networks;

    Sammanfattning : The general aim of the present thesis was to identify and study dynamic contrast-enhanced magnetic resonance imaging (CE-MRI) features that contribute to the diagnosis and may help in predicting prognosis in breast cancer. Study I studied the kinetic and morphological MR features and their diagnostic power were studied in a total of 92 women with 109 histopathologically verified breast lesions. LÄS MER

  7. 5. Aspects of ZnT8 autoimmunity in childhood type 1 diabetes

    Författare :Cecilia K Andersson; Pediatrisk endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Zinc transporter; ZnT8 autoantibodies; HLA; islet cell autoantibodies; GAD65 autoantibodies; IA-2 autoantibodies; insulin autoantibodies; glucose tolerance;

    Sammanfattning : Type 1 diabetes is one of the most common chronic diseases in childhood and adolescence with an increasing incidence worldwide. It is an autoimmune disease with many autoimmune markers, where the zinc transporter 8 autoantibody (ZnT8A) is the most recent autoantibody discovered. LÄS MER