Sökning: "Fusidic Acid"
Visar resultat 6 - 10 av 12 avhandlingar innehållade orden Fusidic Acid.
6. Clostridium difficile-associated diarrhoea - aspects of hospital epidemiology and treatment
Sammanfattning : Clostridium difficile is a spore-forming bacterium that causes antibiotic-associated diarrhoea and is responsible for hospital outbreaks of diarrhoea. In the first study, 173 consecutive isolates of C. LÄS MER
7. Dynamics in Protein Synthesis, Structural Studies of Translation Factors
Sammanfattning : Protein biosynthesis is performed on ribosomes. The ribosome is a complex of ribosomal RNA and proteins forming two subunits. A messenger RNA strand is decoded on the small subunit by charged aminoacyl transfer RNA (aa-tRNA) molecules and each tRNA molecule delivers its amino acid to the growing polypeptide chain on the large subunit. LÄS MER
8. Life will find a way : Structural and evolutionary insights into FusB and HisA
Sammanfattning : How do microbes adapt to challenges from the environment? In this thesis, two distinct cases were examined through structural and biochemical methods. In the first, we followed a real-time protein evolution of HisA to a novel function. The second case was fusidic acid (FA) resistance mediated by the protein FusB in Staphylococcus aureus. LÄS MER
9. Mechanisms and Inhibition of EF-G-dependent Translocation and Recycling of the Bacterial Ribosome
Sammanfattning : The GTPase elongation factor G (EF-G) is an important player in the complex process of protein synthesis by bacterial ribosomes. Although extensively studied much remains to be learned about this fascinating protein. LÄS MER
10. The Physiological Cost of Antibiotic Resistance
Sammanfattning : Becoming antibiotic resistant is often associated with fitness costs for the resistant bacteria. This is seen as a loss of competitiveness against the antibiotic-sensitive wild-type in an antibiotic-free environment. LÄS MER
