Sökning: "FKBP12"

Hittade 4 avhandlingar innehållade ordet FKBP12.

  1. 1. Myocardial ischemia and reperfusion injury, clinical and experimental studies

    Författare :Karin Åström-Olsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardium; ischemia; reperfusion injury; FKBP12; FKBP12.6;

    Sammanfattning : Acute myocardial infarction is the consequence of an occluded nutrient coronary artery. Reperfusion reduces infarct size and enhances the rate of survival. But reperfusion may also, in itself, cause reversible injury, stunning and arrhythmias, as well as irreversible lethal reperfusion injury. LÄS MER

  3. 2. Molecular dynamics studied by NMR relaxation experiments. Characterization of functional dynamics in the FK506 binding protein FKBP12

    Författare :Ulrika Brath; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nuclear magnetic resonance; NMR; FK506; protein dynamics; chemical exchange; spin relaxation; FKBP12; FKBP; isotope labeling;

    Sammanfattning : The presented thesis work is concerned with the study of molecular dynamics using liquid nuclear magnetic resonance (NMR) spectroscopy. Spin relaxation dispersion experiments in the rotating frame (R1ρ) are employed to provide a detailed, atomic-resolution view of protein dynamics. LÄS MER

  4. 3. Oxidative stress and muscle weakness associated with rheumatoid arthritis

    Författare :Maarten Michiel Steinz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Muscle weakness is a common comorbidity of several severe diseases which results in a reduced independence and quality of life and for the afflicted patients. For instance, patients with rheumatoid arthritis (RA), a disease characterized by a chronic inflammation of the joints, commonly report of muscle weakness as a complication. LÄS MER

  5. 4. Peptidyl-prolyl cis-trans Isomerases in the Chloroplast Thylakoid Lumen

    Författare :Anna Edvardsson; Alexander Vener; Bertil Andersson; Per Gardeström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidyl-prolyl isomerase activity; Cyclophilin; FKBP; Immunophilin; Chloroplast Thylakoid Lumen; protein characterization; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The Sun is the ultimate energy source on Earth. Photosynthetic organisms are able to catalyze the conversion of solar energy to chemical energy by a reaction called photosynthesis. In plants, this process occurs inside a green organelle called the chloroplast. LÄS MER