Sökning: "Extracellular phosphorylation"
Visar resultat 11 - 15 av 120 avhandlingar innehållade orden Extracellular phosphorylation.
11. Signal Transduction by Proline-Rich Tyrosine Kinase Pyk2
Sammanfattning : The proline-rich tyrosine kinase (Pyk2) together with focal adhesion kinase (FAK) define a family of non-receptor protein tyrosine kinases that are regulated by diverse stimuli. Activation of Pyk2 has been implicated in multiple signaling events, including modulation of ion channels, activation of MAP kinase cascades and apoptotic cell death. LÄS MER
12. Injury-induced activation of vascular smooth muscle cells. Role of specific gene expression and intracellular signalling pathways
Sammanfattning : Migration and proliferation of smooth muscle cells (SMC) are important events in the development of atherosclerosis and restenosis following angioplastic surgery. It is important to gain further knowledge about the mechanisms regulating SMC form and function in order to understand the underlying disease process. LÄS MER
13. Regulation and physiological role of tyrosine hydroxylase phosphorylation in the striatum
Sammanfattning : Tyrosine hydroxylase (TH) catalyses the conversion of tyrosine to DOPA and is the rate- limiting enzyme in the biosynthesis of catecholamines, a group of neurotransmitters involved in various brain functions. Short-term regulation of TH activity is achieved by phosphorylation of the protein's regulatory domain at three seryl residues in positions 19, 31 and 40. LÄS MER
14. A study of the cytoplasmic domains of C-CAM isoforms : calmodulin binding and phosphorylation
Sammanfattning : C-CAM, a member of the Immunoglobulin Superfamily, was originally identified as an intercellular adhesion molecule, and can mediate cell-cell adhesion by homophilic binding. However, it also appears in high concentrations in luminal, microvillar surfaces. LÄS MER
15. Molecular Tools for Detection and Characterization of Proteins and Extracellular Vesicles in Health and Disease
Sammanfattning : Detecting molecules involved in cancer is critical for cancer research and diagnostics. To achieve this goal, sensitive protein detection is essential to improving the chances of finding, verifying, validating and developing valuable biomarkers. LÄS MER