Sökning: "CoA pathway"

Visar resultat 16 - 20 av 36 avhandlingar innehållade orden CoA pathway.

  1. 16. Structural enzymology of oxalate degradation in Oxalobacter formigenes

    Författare :Catrine L Berthold; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Oxalic acid, as one of nature's most highly oxidised compounds, is toxic to most organisms. It is introduced in the human body in the diet but also as a waste product of cellular metabolism. Mammals do not posses the ability to degrade oxalate and must excrete it in the urine or through the intestine. LÄS MER

  2. 17. Engineering central carbon metabolism with phosphoketolase pathways in Saccharomyces cerevisiae

    Författare :John Hellgren; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; precursor supply; transcriptomics; sustainability; non-oxidative glycolysis; Carbon-conservation; metabolic engineering; platform strain; GATHCYC; proteomics;

    Sammanfattning : We need more efficient biocatalysts to make sustainable microbial production of chemicals and fuels more profitable before they can replace petroleum-based sources. Rewiring the metabolic pathways in the biocatalysts to avoid the loss of carbon as CO2 can aid in improving product yields and thereby the profitability of the process. LÄS MER

  3. 18. Requirement for mevalonate-derived lipids in cell proliferation : a study of the role of polyisoprenoid alcohols

    Författare :Johan Wejde; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mevalonic acid constitutes a key intermediate in the biosynthesis of a number of isoprenoid products. These metabolites include cholesterol and sterol-derived molecules, but also a large number of non-sterol isoprene derivatives. LÄS MER

  4. 19. Metabolic engineering of S. cerevisiae for the production of flavonoids

    Författare :Marta Tous Mohedano; Chalmers tekniska högskola; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microbial cell factories; high-value products; sustainability; cinnamic acid; plant natural products; Genetic engineering; yeast;

    Sammanfattning : The interest in the production of natural products such as flavonoids has been increasing during the last decade. Flavonoids have several attractive bioactivities including antitumoral, antioxidant or antimicrobial properties. To produce these high-value products, we usually recur to chemical synthesis or plant extraction. LÄS MER

  5. 20. Anaerobic degradation of phenol and related aromatics

    Författare :Anna Karlsson; James M. Tiedje; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Aromatic compunds; anaerobic degradation; Fysik; Kemi; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN;

    Sammanfattning : Phenol and other simple aromatic compounds have been found in water leached from landfills, showing that these types of compounds could be either present in disposed waste, or released from it via transformation and degradation processes. Hence, the fate anddegradation potential of such compounds under landfilling conditions is of great concern. LÄS MER