Sökning: "Cetirizine enantiomers"

Hittade 1 avhandling innehållade orden Cetirizine enantiomers.

1. 1. Role of the Blood-Brain Barrier in Stereoselective Distribution and Delay in H1 Receptor Occupancy of Cetirizine in the Guinea Pig Brain

   Författare :Anubha Gupta; Margareta Hammarlund-Udenaes; Niclas E. Jonsson; Joseph W. Polli; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics Pharmacotherapy; Cetirizine enantiomers; Brain distribution; Microdialysis; H1 receptor occupancy; Stereoselective-pharmacokinetics; Farmakokinetik Farmakoterapi; PHARMACY; FARMACI;

   Sammanfattning : Cetirizine, an H1-antihistamine, is prescribed for allergic disorders. It exists as a racemic mixture, with levocetirizine being the active enantiomer. The central nervous system side-effects of H1-antihistamines are caused by their penetration into the brain. LÄS MER