Sökning: "Carbohydrate-protein interactions"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Carbohydrate-protein interactions.
1. Glycoconjugates : synthesis and investigation of carbohydrate-protein interactions
Sammanfattning : To study the functions of glycoconjugates in biological systems reliable and efficient protocols for glycoconjugate synthesis are needed. To reach this goal we have developed methods for solid-phase synthesis of glycoconjugates that can be monitored with gel-phase 19F spectroscopy using fluorinated linkers, building blocks, and protecting groups. LÄS MER
2. Computational Analysis of Carbohydrates : Dynamical Properties and Interactions
Sammanfattning : In this thesis a computational complement to experimental observables will be presented. Computational tools such as molecular dynamics and quantum chemical tools will be used to aid in the interpretation of experimentally (NMR) obtained structural data. LÄS MER
3. Photochemical Surface Functionalization : Synthesis, Nanochemistry and Glycobiological Studies
Sammanfattning : This thesis mainly deals with the development of photochemical approaches to immobilize carbohydrates on surfaces for glycobiological studies. These approaches have been incorporated into a number of state-of-the-art nanobio-platforms, including carbohydrate microarrays, surface plasmon resonance (SPR), quartz crystal microbalance (QCM), atomic force microscopy (AFM), and glyconanomaterials. LÄS MER
4. QCM-D based biosensing – exploring the possibilities
Sammanfattning : We are constantly increasing our understanding of all biological systems and how these highly complex systems interact with each other. The high degree of complexity of these systems can be investigated in greater and greater detail by increasingly sophisticated sensing techniques. LÄS MER
5. Development and Evaluation of Tools to Explore Posttranslational HexNAc-Tyrosine and Mucin-Type O-Glycosylation
Sammanfattning : Glycosylation is the most abundant form of post-translational modification (PTM). Recently, O-glycosylation attracted much attention in the glycoproteomic field due to its association with various diseases, such as pathogenic infections and cancer. LÄS MER