Sökning: "Adaptivt immunförsvar"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Adaptivt immunförsvar.

  1. 1. Intestinal immune cells in health and disease. Dissecting histological characteristics of inflammatory bowel disease and inflamed lung using quantitative immunohistochemical image analysis

    Författare :Manar Alyamani; Adaptivt immunförsvar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IBD; CD; UC; Quantitative imaging; COVID -19; NPP7 Nucleotide phosphodiesterase pyrophosphatase 7; alkaline sphingomyelinase; histopathology; Multiplexed IHC; Immunohistochemical staining; S1P Sphingosine-1-phosphate;

    Sammanfattning : .... LÄS MER

  3. 2. Regulation of the germinal center response by T follicular helper cells and type I interferons

    Författare :Madelene Dahlgren; Adaptivt immunförsvar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Germinal Center; T follicular helper cell; type I interferon; dendritic cell; adjuvant; differentiation; IgG;

    Sammanfattning : The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to B cell follicles. LÄS MER

  4. 3. Intestinal dendritic cell migration and induction of T cell responses

    Författare :Karin Hägerbrand; Adaptivt immunförsvar; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The intestine represents the body’s largest surface exposed to the outer world and is thus a major entry site for pathogens such as bacteria and viruses. The intestinal immune system has the important task of protecting us against infection while maintaining tolerance against the vast amount of commensal microbes populating the intestinal tract and the multitude of foreign antigen present in the diet. LÄS MER

  5. 4. Regulatory properties of dendritic cells and B cells in adaptive immunity

    Författare :Bengt Johansson Lindbom; Adaptivt immunförsvar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; Cellular differentiation; Cytokines; Dendritic cells; B lymphocytes; T lymphocytes;

    Sammanfattning : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. LÄS MER

  7. 5. Costs in the ecology and evolution of the vertebrate immune system

    Författare :Lars Råberg; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cost of resistance; ecological immunology; immunocompetence; Parus caeruleus; transgenic mice; Animal ecology; Djurekologi; blue tit; basal metabolic rate;

    Sammanfattning : A central assumption of theories of the ecology and evolution of immunological defence is that defence has not only benefits (in the form of resistance against parasites), but also costs. The aim of my studies was to investigate the nature and magnitude of costs of the vertebrate immune system, and to examine some of the consequences of these costs. LÄS MER