Sökning: "Äldre för mycket läkemedel"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Äldre för mycket läkemedel.

  1. 1. Blood pressure in very old age : determinants, adverse outcomes, and heterogeneity

    Författare :Bodil Weidung; Yngve Gustafson; Håkan Littbrand; Bo Carlberg; Peter Nordström; Sölve Elmståhl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood pressure; aged 80 and over; hypertension; hypotension; mortality; stroke; gait speed; cognition disorders; dementia; cohort study;

    Sammanfattning : Background: High blood pressure (BP) is the leading risk factor for disease and mortality worldwide. However, risks associated with high BP in very old age (≥ 80 or ≥ 85 years) are not entirely understood, as the majority of scientific studies have been performed with younger populations and existing scientific knowledge about very old individuals is sometimes contradictory. LÄS MER

  2. 2. Dynamic Modelling of Emulsification in High-Pressure Homogenizers

    Författare :Andreas Håkansson; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Population Balance Equations; Emulsification; High-Pressure Homogenization; Computational Fluid Dynamics; Mathematical Modelling.;

    Sammanfattning : Different approaches and sub-models for the modelling of emulsification in a high-pressure homogenizer are reviewed and compared in terms of both practical aspects and how well they describe what is currently known on the emulsification process in general and on high-pressure homogenization in particular. Special effort is devoted to comparing the model developments presented in the appended papers to their alternatives and previous suggestions. LÄS MER

  3. 3. A systematic approach to improving pharmacotherapy in the elderly

    Författare :Anna Bergkvist; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medication reconciliation; medication report; medication errors; LIMM; inpatients; hospital discharge; elderly; Clinical pharmacy; drug related problem; medication review;

    Sammanfattning : The aim of this thesis was to investigate whether a structured and systematic approach on improving pharmacotherapy in the elderly (the LIMM-model) would lead to a more appropriate and accurate drug use in the elderly. The elderly use many drugs and are more prone to suffer from adverse drug reaction. LÄS MER

  4. 4. Central nervous system targets for micturition control

    Författare :Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

    Sammanfattning : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. LÄS MER

  5. 5. Depression in older people with and without dementia : non-pharmacological interventions and associations between psychotropic drugs and mortality

    Författare :Gustaf Boström; Håkan Littbrand; Erik Rosendahl; Peter Nordström; Knut Engedal; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Depression; Dementia; Exercise; Randomized controlled trial; Psychotropic drugs; Mortality; Gender; Residential facilities; Frail elderly; Epidemiology; Cohort study; geriatrik; Geriatrics; sjukgymnastik; Physiotherapy;

    Sammanfattning : The aim of this thesis was to investigate associations between psychotropic drug use and death, associations between functional capacity, dependency in ADL and depression, and to evaluate a non-pharmacological intervention to reduce depressive symptoms, among older people with and without dementia.There is limited knowledge about the risk of death associated with psychotropic drug use among those aged ≥85 years, those with dementia, or those living in residential care facilities; groups that have a higher intake of psychotropic drugs and who are also more prone to adverse drug reactions. LÄS MER