Sökning: "host defence reaction"
Visar resultat 6 - 7 av 7 avhandlingar innehållade orden host defence reaction.
6. Alcohol and inflammation : a study of effects of ethanol on endothelial and epithelial cell functions
Sammanfattning : Although short–term alcohol drinking causes euphoric and stress relieving effects, alcohol abuse is a major risk factor for neurobehavioural, liver and muscle injury as well as reduced host defence with enhanced susceptibility to bacterial infections. Although such reductions also suggest potential use as an anti-inflammatory drug, well known side effects of ethanol limits its clinical use. LÄS MER
7. Studies on molecular properties and functional regulation of terminal leukotriene C4 synthases and cysteinyl-leukotriene receptor signalling in human endothelium
Sammanfattning : The transformation of the unstable intermediate leukotriene (LT) A4 into the glutathione conjugate LTC4, the parent compound of LTD4 and LTE4, is catalysed by leukotriene C4 synthase (LTC4S) as well as microsomal glutathione S-transferase type 2 (MGST2) and type 3 (MGST3). Together, these eicosanoids also known as cysteinyl leukotrienes (cys-LT) are key mediators of immediate hypersensitivity reactions. LÄS MER
