Sökning: "Manuela O Gustafsson Sfetcovici"

Hittade 1 avhandling innehållade orden Manuela O Gustafsson Sfetcovici.

  1. 1. Characterization of ankyrin repeat domain 54 (ANKRD54) and its role on the regulation and subcellular localization of Bruton’s tyrosine kinase (BTK)

    Författare :Manuela O Gustafsson Sfetcovici; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bruton's tyrosine kinase (BTK) is an important cytoplasmic signaling protein, where the kinase activity plays a pivotal role in the development, proliferation and differentiation of B-cell lineages. Ankyrin repeat domain 54 (ANKRD54) is a nuclear-resident adaptor protein, where the ankyrin domain repeats are critical for specific protein-protein interaction, while the NLS and NES motifs control the nucleo-cytoplasmic shuttling ability. LÄS MER