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  1. 1. Human truncated thioredoxin (Trx80) as a novel mitogenic cytokine for white blood cells

    Författare :Klas Pekkari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Thioredoxin (Trx) is a 12 kDa protein present in all species with a well-conserved active site sequence comprising -Cys-Gly-Pro-Cys-, which catalyzes oxido-reductase reactions. Trx regulates the activity of transcription factors and intracellular signalling pathways, and secreted Trx is a co-cytokine with several interleukins. LÄS MER