Sökning: "Klas Linderholm"
Hittade 1 avhandling innehållade orden Klas Linderholm.
1. Kynurenic acid in psychiatric disorders : studies on the mechanisms of action
Sammanfattning : Kynurenic acid, a metabolite of tryptophan along the kynurenine pathway, is an endogenous antagonist at NMDA- and α7* nicotinic acetylcholine- (α7*nACh) receptors. Previous studies have shown that elevated levels of endogenous kynurenic acid are associated with an increased firing of midbrain dopamine neurons as well as a reduced prepulse inhibition (PPI), a behavioral model for sensorimotor gating. LÄS MER
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