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1. 1. Alzheimer disease : studies on Abeta and gamma-secretase in human brain

   Författare :Hedvig Welander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Alzheimer disease (AD) is a devastating neurodegenerative disorder and the most prevalent form of dementia. One hallmark of the disease is the extracellular deposition of amyloid beta-peptide (Abeta) into senile plaques in the brain. Biochemical and genetic studies reveal Abeta as a key player in AD pathogenesis. LÄS MER