Sökning: "Colon cancer biomarkers"

Visar resultat 21 - 25 av 27 avhandlingar innehållade orden Colon cancer biomarkers.

  1. 21. Stroma and vessel characteristics in cancer : impact on prognosis and response to treatment

    Författare :Artur Mezheyeuski; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A series of pre-clinical and clinical studies imply vessel and pericyte status as determinants of tumor growth, metastasis and response to treatment. These studies thus imply biomarkerpotential of these features. Earlier studies of vessels and pericytes have largely applied semiquantitative approaches. LÄS MER

  3. 22. NotI genome scanning to identify unknown cancer associated genes in major human epithelial malignancies

    Författare :Klas Haraldson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epithelial cancers cause many deaths every year. Changes in the genes of human chromosome 3 are particularly common in epithelial cancers in several organs. Alterations in DNA methylation is one of the best known epigenetic changes in cancer. LÄS MER

  4. 23. Multivariate analysis of cancer proteomics data : towards a biological systems view and understanding

    Författare :Lina Hultin Rosenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Important aims of cancer proteomics include gaining better understanding of cancer biology and identifying cancer biomarkers. Mass spectrometry (MS) based shotgun proteomics allow for identification and quantification of thousands of proteins in complex human samples. LÄS MER

  5. 24. Proteomic analysis of DNA damage induced stress signaling with focus on p53 : S100A6 regulation, function and potential as biomarker in lung cancer and as a novel therapeutic target

    Författare :Lukas Orre; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In this thesis powerful proteomics methods were used to reveal novel proteins involved in the cellular response to DNA damaging treatment. The goal was to find proteins with potential as biomarkers for prediction of cancer prognosis and response to cancer therapy, but also to find potential novel targets of cancer therapy. LÄS MER

  7. 25. Decoding the tumor microenvironment : a B-cell and macrophage perspective

    Författare :Vanessa F Boura; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The immune system plays a role in many different functions in our body, and disease is no exception. Cancer is one of the biggest challenges of the twenty first century and vast efforts have been made to understand this disease. LÄS MER