Sökning: "Aspartate Aminotransferases"

Hittade 3 avhandlingar innehållade orden Aspartate Aminotransferases.

1. 1. On evaluation of organ damage in perinatal asphyxia : an experimental and clinical study

   Författare :Mathias Karlsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Perinatal asphyxia; hypoxia-ischemia; hypothermia; pig; lactate dehydrogenase; aminotransferases;

   Sammanfattning : Leakage of intracellular enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) signalling multi organ dysfunction (MOD) is seen together with hypoxic ischemic encephalopathy (HIE) after perinatal asphyxia. Hypothermia (HT) can attenuate HIE following perinatal asphyxia and hypoxia-ischemia (HI) but the neuroprotective efficacy falls dramatically the longer the delay in initiating HT. LÄS MER

3. 2. The bioenergetic roles of PGC-1α1, kynurenines, and GPR35 in exercise and obesity

   Författare :Shamim Dadvar; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Obesity is a major cause of medical comorbidity with detrimental effects on health span. Fundamentally, obesity is a condition of disrupted energy metabolism, where energy intake chronically exceeds expenditure. Over time, this disruption causes a systemic low-grade inflammation and impairs energy homeostasis. LÄS MER

4. 3. Mitochondria and its role in metabolic regulation and skeletal muscle function in healthy and disease conditions

   Författare :Zhengye Liu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Skeletal muscle function is critical for our overall health and to be able to perform daily activities. Skeletal muscle has the ability to adapt to various stimuli and mitochondria are known to play an important role in these adaptation processes. LÄS MER