Sökning: "aminotransferases"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet aminotransferases.

  1. 1. On evaluation of organ damage in perinatal asphyxia : an experimental and clinical study

    Författare :Mathias Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Perinatal asphyxia; hypoxia-ischemia; hypothermia; pig; lactate dehydrogenase; aminotransferases;

    Sammanfattning : Leakage of intracellular enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) signalling multi organ dysfunction (MOD) is seen together with hypoxic ischemic encephalopathy (HIE) after perinatal asphyxia. Hypothermia (HT) can attenuate HIE following perinatal asphyxia and hypoxia-ischemia (HI) but the neuroprotective efficacy falls dramatically the longer the delay in initiating HT. LÄS MER

  3. 2. The bioenergetic roles of PGC-1α1, kynurenines, and GPR35 in exercise and obesity

    Författare :Shamim Dadvar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obesity is a major cause of medical comorbidity with detrimental effects on health span. Fundamentally, obesity is a condition of disrupted energy metabolism, where energy intake chronically exceeds expenditure. Over time, this disruption causes a systemic low-grade inflammation and impairs energy homeostasis. LÄS MER

  4. 3. Skeletal muscle PGC-1α1 and KAT enzymes at the intersection between depression and metabolic disease

    Författare :Leandro Z Agudelo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Depression and metabolic diseases are leading causes of disability and major contributors to socioeconomic burden worldwide. Physical activity exerts many beneficial effects that confer direct health improvement in individuals suffering from these disorders. LÄS MER

  5. 4. Diabetes, obesity and exercise in skeletal muscle : effects on gene expression and DNA methylation

    Författare :Jonathan Mudry; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Type 2 diabetes, obesity and depression are growing concerns for human health. Physical exercise is a known protective factor against these disorders, although the underlying mechanisms are incompletely understood. LÄS MER

  7. 5. Chronic hepatitis B in children

    Författare :Ann Söderström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Chronic hepatitis B affects more than 350 million people. In areas of high and intermediate endemicity, hepatitis B virus (HBV) infection is mainly contracted in the perinatal period or early childhood, and many of them become chronic carriers. LÄS MER