Sökning: "tumor cells"

Visar resultat 1 - 5 av 1503 avhandlingar innehållade orden tumor cells.

  1. 1. Studies of the tumor microenvironment : Local and systemic effects exerted by the cross-talk between tumor and stroma cells in pancreatic cancer

    Författare :Vegard Tjomsland; Marie Larsson; Arne Östman; Linköpings universitet; []
    Nyckelord :Pancreatic cancer; cancer associated fibroblasts; dendritic cells; IL-1alpha; tumor microenvironment; inflammation; bukspottkörtelcancer; Bukspyttkjertel kreft; MEDICINE; MEDICIN;

    Sammanfattning : Pancreatic cancer is one of the most lethal cancers and despite all research efforts the last 50 years, there are still no effective therapy for this terrible disease. Until quite recently most research in the field of pancreatic duct adenocarcinoma (PDAC) was focused on the tumor cells and mechanisms essential for their proliferation and survival. LÄS MER

  2. 2. Inflammatory Cells and Mediators in the Tumor Microenvironment of Breast Cancer

    Författare :Roni Allaoui; Malmö Cancerimmunologi; []
    Nyckelord :Breast cancer; tumor stroma; cancer-associated fibroblasts; DAMP; inflammatory mediators; myeloid-derived supressor cells; toll-like receptors; triple-negative breast cancer; tumor infiltrating lymphocytes; tumor microenvironment;

    Sammanfattning : .... LÄS MER

  3. 3. Modeling glioblastoma heterogeneity to decipher its biology

    Författare :Yuan Xie; Lene Uhrbom; Massimo Squatrito; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma multiforme; biobank; GBM cells; cell of origin; LGR5; OPCs;

    Sammanfattning : Glioblastoma multiforme (GBM) is the most common and lethal form of primary brain tumor that mainly affects adults. GBM displays remarkable intra- and inter-tumoral heterogeneity and contains a subpopulation of cells named glioma stem cells that is believed to be responsible for tumor maintenance, progression and recurrence. LÄS MER

  4. 4. Astroglial Cells : Role in Neurodegenerative-Inflammatory Processes in the Central Nervous System

    Författare :Gun Eriksson; Karl Åkerman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : Inflammatory processes, mediated by the pro-inflammatory cytokines interleukin (IL) -1a/b, tumor necrosis factora(TNFa), IL-6 and excitotoxic actions of glutamate, are proposed to be implicated in neurodegenerative diseases, such as Alzheimer's disease.A neurotoxic fragment ofb-amyloid,bA25-35, was shown to induce a reactive phenotype of primary astrocytes and microglial cells in a time-dependent manner. LÄS MER

  5. 5. The tumor immune microenvironment and clinical outcome in patients with esophageal and gastric adenocarcinoma

    Författare :Maria C Svensson; Personlig patologi och cancerbehandling; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin och hälsovetenskap; tumor immune microenironment; Esophageal cancer; Gastric cancer; prognosis; Prediction; Adenocarcinoma; T cells; B cells; NK cells; tumor-associated macrophage TAM ; PD-L1; PD-1;

    Sammanfattning : .... LÄS MER