Sökning: "Esophageal cancer"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden Esophageal cancer.

  1. 1. Genomic Profiling, Mutations and Deranged Signaling in Esophageal Cancer and Hereditary Colorectal Cancer

    Författare :Anna Isinger Ekstrand; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal cancer; hereditary cancer; HNPCC; copy number analysis; CGH; gene expression; Wnt; PIK3CA; CHEK2; gastric cancer; colorectal cancer;

    Sammanfattning : Esophageal cancer and colorectal cancer represents two major types of gastrointestinal tumors. Though refined surgery and introduction of novel chemotherapeutics have improved outcome, more than 2500 Swedes die from these diseases every year. Novel markers for early diagnosis, prognosis and treatment prediction are therefore needed. LÄS MER

  3. 2. The tumor immune microenvironment and clinical outcome in patients with esophageal and gastric adenocarcinoma

    Författare :Maria C Svensson; Personlig patologi och cancerbehandling; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin och hälsovetenskap; tumor immune microenironment; Esophageal cancer; Gastric cancer; prognosis; Prediction; Adenocarcinoma; T cells; B cells; NK cells; tumor-associated macrophage TAM ; PD-L1; PD-1;

    Sammanfattning : .... LÄS MER

  4. 3. Towards improved oncological treatment of esophageal and gastric cancer. Clinical and translational studies

    Författare :David Borg; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal adenocarcinoma; Gastric cancer; PODXL; Prognosis; Prediction; Chemotherapy dose intensity; Dysphagia; Radiotherapy;

    Sammanfattning : BackgroundThe overall aim of this thesis was to improve the oncological treatment strategies in esophageal and gastric adenocarcinoma (EGAC). Podocalyxin-like protein 1 (PODXL) has been associated with poor prognosis in other cancers and we wanted to investigate its potential role as a prognostic and predictive biomarker in resectable EGAC. LÄS MER

  5. 4. Esophageal and Gastroesophageal Junctional Cancer : Improving Patient selection, Treatment and Care

    Författare :Christine Jestin Hannan; Jakob Hedberg; Gustav Linder; Magnus Sundbom; Guillaume Piessen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal cancer; Lymphadenectomy; Geographical differences; Atelectasis; Multidisciplinary Cancer Conference;

    Sammanfattning : Esophageal cancer is the sixth most common cause of cancer-related death. Choice of surgical approach and individualized treatment is crucial. The aims of this thesis were to evaluate the introduction of minimally invasive esophagectomy (MIE) regarding oncological results and postoperative complications. LÄS MER

  7. 5. Esophageal- and Gastroesophageal Junctional Cancer : Aspects on Staging, Treatment and Results

    Författare :Gustav Linder; Jakob Hedberg; Magnus Sundbom; Wilhelm Graf; Bas P.L. Wijnhoven; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal cancer; Education level; Tonometry; Lymphadenectomy; PET MRI; Kirurgi; Surgery;

    Sammanfattning : Esophageal- and gastroesophageal junctional (GEJ) cancer is the sixth cause of cancer-related death worldwide. Some improvements in care are attributed to nationwide disease-specific registries, preoperative staging and increased understanding of mechanisms affecting patient selection. LÄS MER