Sökning: "skin disease"
Visar resultat 1 - 5 av 419 avhandlingar innehållade orden skin disease.
1. Positional Cloning of Disease Causing Genes : A Genetic Study of Obesity, Ichthyosis Prematurity Syndrome and Meniere's Disease
Sammanfattning : Positional cloning is a method to identify genes from their position in the genome without prior knowledge about function. We used this approach to investigate the basis for three distinct genetic disorders; Obesity, Ichthyosis Prematurity Syndrome and Meniere's disease. LÄS MER
2. Darier disease : more than skin deep
Sammanfattning : Darier disease (DD) is a severe, inherited dermatological disorder with a characteristic clinical and histopathological appearance. It is caused by mutations in the ATP2A2 gene, encoding a Ca2+ pump in the endoplasmic reticulum, Sarco/Endoplasmic Reticulum Ca2+-ATPase 2 (SERCA2), which has been found to be an essential regulator of cellular Ca2+ homeostasis. LÄS MER
3. Hereditary ichthyosis : Causes, Skin Manifestations, Treatments and Quality of Life
Sammanfattning : Hereditary ichthyosis is a collective name for many dry and scaly skin disorders ranging in frequency from common to very rare. The main groups are autosomal recessive lamellar ichthyosis, autosomal dominant epidermolytic hyperkeratosis and ichthyosis vulgaris, and x-linked recessive ichthyosis. LÄS MER
4. The limbic-hypothalamic-pituitary-adrenal axis in Alzheimer's disease
Sammanfattning : Dysfunction of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis is a common finding in advanced dementia. In this study, the function of the LHPA axis at different levels was investigated in patients with dementia and in healthy elderly.A subtle disturbance in the feedback regulation of the LHPA axis was found in patients with early (i.e. LÄS MER
5. Aspects of Microbial Influence on Skin Disease
Sammanfattning : The skin constitutes an effective barrier mediating protection against environmental danger and foreign substances. At the surface of the skin, the residential microorganisms grow as small colonies and consist of various non-pathogenic bacteria, fungi and viruses. LÄS MER