Sökning: "sertraline"

Visar resultat 1 - 5 av 20 avhandlingar innehållade ordet sertraline.

1. 1. Psychotropic Pharmaceuticals in Aquatic Systems: An Ecological Perspective

   Författare :Melanie Hedgespeth; Enhet akvatisk ekologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ecotoxicology; aquatic; trophic level; pharmaceutical; SSRI; beta-blocker; sertraline; fluoxetine; propranolol; fish; daphnia; snail; predator; prey; behavior; life history; multiple stressor;

   Sammanfattning : Psychotropic pharmaceuticals have been shown to exert a variety of sublethal effects on non-target organisms, even at low concentrations found in the environment (ng/L to µg/L); hence, the aim of my research has been to determine the individual-level effects of psychotropic pharmaceuticals (the selective serotonin reuptake inhibitors sertraline and fluoxetine, and the β-blocker propranolol) on behavioral and life history traits in freshwater organisms. Further, this research was directed towards assessing the potential large-scale impacts of these effects on population growth and predator-prey interactions (with community-level implications) via the application of traditional, ecological concepts and models. LÄS MER

3. 2. Long-term outcomes of obsessive-compulsive disorder in children and adolescents

   Författare :Karin Melin; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescent; child; cognitive behavioral therapy; follow-up; obsessive-compulsive disorder; sertraline; symptom assessment; self-assessment;

   Sammanfattning : Aim: The overall aim of this thesis is to investigate the long-term course and outcome of pediatric OCD following evidence-based treatment of pediatric OCD. Outcome is assessed with regard to severity of OCD symptoms (Studies I-III), psychosocial functioning (Studies I & II), and depressive symptoms (Study II). LÄS MER

4. 3. Chemo-enzymatic cascades for the synthesis of chiral high-value chemicals

   Författare :Lisa Marx; Per Berglund; Sabine Flitsch; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : Chiral amines are frequent in today´s top selling pharmaceuticals. Classical organic synthesis of pharmaceuticals is often work intensive involving many synthesis steps, the use of protection group chemistry, heavy metal catalysts and chiral crystallization techniques. LÄS MER

5. 4. Clinical and Pharmacological Aspects of Selective Serotonin Reuptake Inhibitors in the Treatment of Depression in Old Age

   Författare :Jöns Lundmark; Finn Bengtsson; Leif Lindström; Linköpings universitet; []
   Nyckelord :Serum concentrations; cerebrospinal fluid; pharmacokinetics; selective serotonin reuptake inhibitors; therapeutic drug monitoring; elderly; depression; pharmaceutical economics; MEDICINE; MEDICIN;

   Sammanfattning : Objective: The aim of the present thesis is to examine the pharmacokinetic and biochemical effects of the selective serotonin reuptake inhibitors (SSRIs) in the elderly.Background: Symptoms of depression are found in up to 15% of the elderly and the prevalence of major depression is reported to be about 3%. LÄS MER

7. 5. Psychotropic drug treatment during pregnancy and lactation : effects on mother and child

   Författare :Essi Whaites Heinonen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The common major depressive disorder and anxiety disorders are often treated with antidepressants. Treatment with mood-stabilizers and antipsychotics are important for pregnant women with bipolar and psychotic disorders, as these women are at risk of postpartum psychosis and even suicide if not treated. LÄS MER