Sökning: "remodelling"

Visar resultat 16 - 20 av 200 avhandlingar innehållade ordet remodelling.

1. 16. Chromatin remodelling in Pol I and III transcription

   Författare :Erica Cavellán; Ann-Kristin Östlund Farrants; Gernot Längst; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Cellbiologi;

   Sammanfattning : Compaction of chromosomes in the eukaryotic cell is due to interactions between DNA and proteins and interactions between proteins. These two types of interaction form a dynamic structure, known as "chromatin". The condensation of chromatin must be carefully regulated, since the structure is an obstacle for factors that need access to the DNA. LÄS MER

3. 17. Fluid biomarkers of extracellular matrix remodelling across neurological diseases

   Författare :Karolina Minta; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; extracellular matrix; idiopathic normal pressure hydrocephalus; immunoassay; mass spectrometry; radiation-induced brain injury; traumatic brain injury; vascular dementia;

   Sammanfattning : Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. LÄS MER

4. 18. Extracellular Matrix Remodelling-Proteoglycan and collagen turnover in arthritis

   Författare :Anette Bjärdahlen; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arthritis; collagen; cartilage; myofibroblasts; pannus; proteoglycan; Skeleton; muscle system; rheumatology locomotion; reumatologi; Skelett; muskelsystem;

   Sammanfattning : Rheumatoid arthritis is a chronic, inflammatory and systemic disease characterised by joint destruction and pannus formation. To enlarge the understanding how pannus and granulation tissue are formed two animal models were used; one using cartilage wrapped in cotton and implanted into a rat air pouch (AP) and one where mBSA induced arthritis (AIA) was performed. LÄS MER

5. 19. Atherosclerosis in 64-year-old women with diabetes mellitus and impaired glucose tolerance

   Författare :Gerhard Brohall; Göteborgs universitet; []
   Nyckelord :Systematic review; Atherosclerosis; Type-2 diabetes; IMT; Vascular remodelling; IGT;

   Sammanfattning : Atherosclerosis in 64-year-old women with diabetes mellitus and impaired glucose tolerance The incidence of obesity and type-2 diabetes (t2D) is rising around the world. T2D is accompanied by an increased risk of macrovascular, atherosclerotic diseases. LÄS MER

7. 20. A methodological platform to study molecular biocompatibility of biomaterials. Experimental and clinical studies

   Författare :Maria Lennerås; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osseointegration; titanium; inflammation; cell recruitment; cell adhesion; bone regeneration; bone remodelling; gene expression; immunohistochemistry; histomorphometry; removal torque; ultrastructure; FACS; protein profiling; transfemoral amputation; abutment; percutaneous; bacteria; clinical signs;

   Sammanfattning : The aim of this project was to develop a methodological platform in order to advance our scientific understanding of the mechanisms of osseointegration. Screw-shaped, titanium implants, with different surface properties, were inserted in the rat tibia, or incubated in mono- or co-culture of human monocytes and MSCs. LÄS MER