Sökning: "real-world population"

Visar resultat 1 - 5 av 69 avhandlingar innehållade orden real-world population.

1. 1. Somatic and occupational outcomes in adult ADHD : epidemiology studies based on real-world data

   Författare :Lin Li; Henrik Larsson; Zheng Chang; Qi Chen; Mark Taylor; Argyris Stringaris; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ADHD; Comorbidities; Obesity; Dietary habits; ADHD medication; Cardiovascular disease; Epidemiology; Casual inference; Adults;

   Sammanfattning : Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders, characterized by inattention or hyperactivity–impulsivity, or both. ADHD is a multifactorial disorder influenced by the complex interplay between genetic and environmental risk factors, but a detailed understanding of the causal status of these factors is lacking. LÄS MER

3. 2. Population-based studies in Myelodysplastic syndromes : Prognostic scores, socioeconomic status, and therapy-related disease

   Författare :Daniel Moreno Berggren; Elisabeth Ejerblad; Sören Lehmann; Martin Jädersten; David Bowen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myelodysplastic syndromes; Chronic myelomonocytic leukaemia; Prognostication; Comorbidity; Therapy-related disease; Real-world data; Population-based studies; Medicinsk vetenskap; Medical Science;

   Sammanfattning : The aim of this thesis was to expand the epidemiological knowledge of the haematological malignancy MDS and the related condition chronic myelomonocytic leukaemia (CMML). Using nationwide registers, the papers in this thesis address aspects of prognostication, comorbidity, socioeconomic status, and therapy-related disease, using a population-based approach. LÄS MER

4. 3. Lifestyle Intervention from a Health Economics Perspective

   Författare :Sanjib Saha; Hälsoekonomi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lifestyle intervention; decision-analytic model; differences-in-differences approach; real-world;

   Sammanfattning : Abstract The aim of this thesis was to perform health economic analyses of lifestyle intervention for people at a high risk of cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). The results can help decision-makers to make informed decisions over implementing lifestyle intervention, taking several dilemmas into consideration. LÄS MER

5. 4. Real-world outcomes in oncology : assessing the value of rewardable innovation

   Författare :Nahila Justo; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Recent years have seen a remarkable expansion of therapeutic options available for many forms of cancer. Evidence for the efficacy of these treatments have mainly come from randomized controlled trials, however questions often remain regarding the actual use, effectiveness and value of innovative therapies when used under the circumstances of routine clinical practice. LÄS MER

7. 5. Bridging the gap between clinical trials and clinical practice : sacubitril-valsartan in heart failure as a model

   Författare :Helena Norberg; Krister Lindmark; Ellinor Bergdahl; Eva-Lotta Glader; Björn Wettermark; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systematic implementation; healthcare quality improvement; chronic disease management; heart failure; sacubitril-valsartan; real-world population; sex differences; kardiologi; Cardiology;

   Sammanfattning : When novel treatments prove more effective than standard therapies, a swift and effective implementation is needed to reach cost-effectiveness and to benefit eligible patients. Meanwhile, women and elderly are often under-represented in clinical trials, which creates a knowledge gap on how to optimize treatment in clinical practice. LÄS MER