Sökning: "novel traits"
Visar resultat 6 - 10 av 167 avhandlingar innehållade orden novel traits.
6. Beyond GWAS : Novel Methods and Resources for Genetic Epidemiology
Sammanfattning : Since the first human genome assembly’s release, our knowledge of the genetic architecture of complex traits and diseases has grown steadily. Genome-wide association studies (GWAS) played a major role but are limited to common traits and single-nucleotide polymorphisms (SNPs). LÄS MER
7. Gene mapping of reproduction traits in dairy cattle
Sammanfattning : In this thesis my aims were to map genes affecting reproduction in cattle and to explore the correlated effect of these genes on yield traits. This knowledge is expected to provide novel insights into the biological processes underlying reproduction traits and to identify individual causal polymorphisms or genetic markers for practical application in marker-assisted and genomic selection strategies. LÄS MER
8. Metaproteogenomics-guided enzyme discovery : Targeted identification of novel proteases in microbial communities
Sammanfattning : Industrial biotechnology is a large and growing industry as it is part of establishing a “greener” and more sustainable bioeconomy-based society. Using enzymes as biocatalysts is a viable alternative to chemicals and energy intense industrial processes and is en route to a more sustainable industry. LÄS MER
9. Functional Genomics of Bone Metabolism : Novel Candidate Genes Identified by Studies in Chicken Models
Sammanfattning : Osteoporosis is a disease that leads to decreased bone mineral density (BMD), an altered bone micro-architecture and fragile bones. The disease is highly heritable and numerous genes are thought to be involved, making it difficult to identify the causative genetic elements. LÄS MER
10. Novel statistical methods for genome-wide association summary statistics
Sammanfattning : A general objective of genetic studies is to understand the genetic basis of complex traits such as height, body mass index (BMI), disease endpoints, etc. Such researches have been facilitated due to the completion of the human genome project and developments of high-throughput technologies. LÄS MER