Sökning: "pronucleus"

Hittade 3 avhandlingar innehållade ordet pronucleus.

  1. 1. Three dimensional mathematical modelling of pronuclei migration for the mouse

    Författare :Sofia Tapani; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fertilisation process; pronucleus; dynamical simulation; SDE; correlation; CUSUM; microtubule; confocal microscopy; dynamical simulation;

    Sammanfattning : The main question addressed in this thesis is what happens between the moment when the sperm enters the egg and the fusion of the male and the female pronuclei. Orientation of the apposing pronuclei most likely plays a decisive role in the polarity of the developing embryo. LÄS MER

  3. 2. Stochastic modelling and analysis of early mouse development

    Författare :Sofia Tapani; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; correlation; CUSUM; mouse; non-stationarity; pronucleus; stochastic differential equation; time series; wavelet decomposition; yeast; CUSUM;

    Sammanfattning : The aim of this thesis is to model and describe dynamical events for biological cells using statistical and mathematical tools. The thesis includes five papers that all relate to stochastic modelling of cells. LÄS MER

  4. 3. Amyloid precursor protein with the Alzheimer´s disease 670/671 mutation : animal and cellular models

    Författare :Ewa Kloskowska; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The amyloid precursor protein (APP) and it s derivatives play a key role in the pathogenesis of Alzheimer s disease (AD), which is characterized by the presence of multiple aggregates of an APP proteolytic product, Ab, and tau protein in the brains of affected patients. Clinically the disease is manifested by a progressive loss of memory and executive functions. LÄS MER