Sökning: "miR-34c"

Hittade 4 avhandlingar innehållade ordet miR-34c.

  1. 1. A microscopic investigation of miR-34c and miR-205 in Prostate Cancer

    Författare :Zandra Hagman; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; prostate cancer; androgen receptor; MET; HGF; miR-34c; miR-205; AGO2-RIP-Chip; noncoding RNA;

    Sammanfattning : The complex genetics of cancer allows tumors to grow and spread undeterred by the control mechanisms of the cell. The importance of protein-coding genes in tumorigenesis is well established. LÄS MER

  3. 2. Regulation of cellular growth and identification of stromal gene signatures in breast cancer

    Författare :Sofia Winslow; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; cellular stress; proliferation; PKCα; G3BP; PMP22; miR-34c; gene expression profiles; stroma;

    Sammanfattning : Normal tissue is tightly controlled to keep a balance between reproduction and elimination of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. LÄS MER

  4. 3. Axl RTK and microRNAs in urogenital cancers

    Författare :Helena Fritz; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This thesis is based on four projects focused on the Axl receptor tyrosine kinase (RTK) and microRNAs in clear cell renal cell carcinoma (ccRCC) and in prostate cancer (PCa). Paper I focuses on differentially expressed microRNAs in ccRCC. LÄS MER

  5. 4. The roles of microRNAs in skin wound healing

    Författare :Xi Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Skin is an essential biological barrier of the human body, and wound healing is the fundamental physiological process to keep its integrity. Chronic non-healing wounds are growing socioeconomic and health concerns, which longs for more understanding of their pathophysiology to discover effective treatments. LÄS MER